[42F] With chronic lower body pain and flu-like symptoms

Patient Description

A 42-year-old female has been experiencing lower body pain and flu-like symptoms every night for the past two years. The pain is described as aching and is quite severe, rated 8 out of 10. It worsens at night and affects her ability to perform daily tasks like cleaning and going to the store. She also reports feeling weak, feverish, and tired all the time, with the weakness getting worse at night, making it difficult to walk or get up from a chair. Additionally, she has experienced muscle and joint pain, sometimes with swelling and redness in her legs and ankles. She has not noticed any rashes, skin changes, or hair loss. She has lost weight and has been eating less for about five months. She experiences chills but not night sweats. She has not used any substances like alcohol, tobacco, or recreational drugs, and there have been no significant changes in her diet or recent travel. Her family history includes cancer, although she is not sure about the specifics. Her menstrual history is normal, and she has not noticed any changes in her cycle over the past two years. She has chronic lupus and allergies to penicillin, sulfa, and ibuprofen. She is not currently taking any medications. Over the past month, she has experienced episodes of sudden nausea and has vomited a few times. This is a new symptom that wasn't present during the past two years of her other symptoms. The vomiting is sudden, and she has not found anything that helps to relieve her nausea or makes it easier for her to eat.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your symptoms:

Lower Body Pain, Weakness, and Flu-like Symptoms

  • Lupus Flare-Up: Given your history of lupus, it's possible that your symptoms are related to a flare-up of this condition. Lupus can cause widespread pain, fatigue, and flu-like symptoms.
  • Fibromyalgia: This condition often coexists with lupus and can cause chronic pain, fatigue, and flu-like symptoms.
  • Chronic Fatigue Syndrome: This condition can cause severe fatigue, muscle pain, and flu-like symptoms that worsen with activity.

Nausea and Vomiting

  • Gastrointestinal Issues: Conditions like gastritis, peptic ulcers, or gastroesophageal reflux disease (GERD) can cause nausea and vomiting.
  • Medication Side Effects: Although you're not currently taking any medications, it's worth considering any recent changes in diet or supplements that might be contributing to these symptoms.
  • Infections: Viral or bacterial infections can cause sudden nausea and vomiting.

Weight Loss and Reduced Appetite

  • Nutritional Deficiencies: Chronic illness and reduced food intake can lead to nutritional deficiencies, which can exacerbate your symptoms.
  • Depression or Anxiety: These mental health conditions can also cause changes in appetite and weight loss.

Unifying Diagnoses

  • Lupus: Many of your symptoms, including pain, fatigue, and gastrointestinal issues, could be related to lupus.
  • Fibromyalgia: This condition could explain the chronic pain and fatigue.
  • Chronic Fatigue Syndrome: This could be a unifying diagnosis for your severe fatigue and flu-like symptoms.

What you can do

Lower Body Pain, Weakness, and Flu-like Symptoms

  • Consult Your Doctor: It's important to see your healthcare provider to discuss these symptoms, especially given your history of lupus. They may recommend blood tests, imaging studies, or referrals to specialists.
  • Manage Lupus: Follow your doctor's advice for managing lupus, which may include medications, lifestyle changes, and regular monitoring.
  • Pain Management: Over-the-counter pain relievers like acetaminophen (Tylenol) can help, but avoid NSAIDs like ibuprofen due to your allergy. Heat or cold packs may also provide relief.

Nausea and Vomiting

  • Stay Hydrated: Drink small sips of water, clear broth, or an electrolyte solution to stay hydrated.
  • Eat Small, Frequent Meals: Try eating small, bland meals throughout the day to avoid triggering nausea.
  • Avoid Triggers: Identify and avoid foods or smells that trigger your nausea.

Weight Loss and Reduced Appetite

  • Nutrient-Dense Foods: Focus on eating nutrient-dense foods like fruits, vegetables, lean proteins, and whole grains.
  • Consult a Dietitian: A registered dietitian can help you develop a meal plan that meets your nutritional needs.
  • Monitor Your Weight: Keep track of your weight and any changes in your symptoms using the MDandMe journal.

What you should look out for

Given the severity and duration of your symptoms, it's important to seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Severe or Worsening Pain: If your pain becomes unbearable or significantly worsens.
  • Persistent Vomiting: If you cannot keep any food or liquids down.
  • Signs of Infection: Such as high fever, chills, or new rashes.
  • Severe Weakness or Fatigue: If you find it increasingly difficult to perform daily activities.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and treatment plan. If you have more questions or need further assistance, feel free to continue the conversation.

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4 mo ago

People Also Ask


What are common symptoms of a lupus flare-up?

Common symptoms of a lupus flare-up include joint pain and swelling, fatigue, fever, skin rashes, and flu-like symptoms. It's important to monitor these symptoms and consult with a healthcare provider for appropriate management.


How can fibromyalgia affect someone with lupus?

Fibromyalgia can exacerbate symptoms in someone with lupus by adding chronic widespread pain, fatigue, and sleep disturbances. It can make managing lupus more challenging and may require a comprehensive treatment approach.


What dietary changes can help manage nausea and vomiting?

To manage nausea and vomiting, it's helpful to eat small, bland meals throughout the day, stay hydrated with clear fluids, and avoid foods or smells that trigger nausea. Ginger tea or peppermint may also help soothe the stomach.


What are the potential causes of sudden weight loss and reduced appetite?

Sudden weight loss and reduced appetite can be caused by nutritional deficiencies, chronic illnesses like lupus, mental health conditions such as depression or anxiety, and gastrointestinal issues. It's important to address these symptoms with a healthcare provider to determine the underlying cause.


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