[27F] With chronic rash and itchy eyes

Patient Description

A 27-year-old female has been experiencing a continuous rash with welts all over her body for almost a year, occurring daily. The rash is exacerbated by stress, and Benadryl has not provided relief. Additionally, she reports persistent itchiness in her eyes and eyelids throughout the day, with no associated swelling or redness. There are no difficulties with breathing, facial swelling, or known medication allergies. The patient has a latex allergy but no recent exposure. Family history is significant for lupus, though she has not been evaluated for autoimmune conditions. She was diagnosed with an anxiety disorder in 2009. Currently, she is not on any prescription medications but takes Tylenol and Benadryl daily, with an unspecified dosage.

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Arora's Assessment

What might be happening

Based on your symptoms, here are some possible explanations:

  • Chronic Urticaria (Hives): This condition involves persistent itchy welts on the skin. Stress can be a trigger, and it often requires management with antihistamines or other medications prescribed by a doctor.
  • Allergic Reaction: Although you haven't identified a specific trigger, ongoing exposure to an allergen could cause these symptoms. Latex is a known allergy, but since there's no recent exposure, consider other environmental factors.
  • Autoimmune Conditions: Given your family history of lupus, it's possible that an autoimmune condition could be contributing to your symptoms. These conditions can cause skin rashes and other systemic symptoms.

Typical treatments might include antihistamines, corticosteroids, or other medications to manage symptoms. Testing could involve allergy tests or blood tests to rule out autoimmune conditions.

What you can do

  1. Consult a Healthcare Provider: It's important to see a doctor for a thorough evaluation, especially given the duration and persistence of your symptoms.
  2. Track Symptoms: Use MDandMe to journal your symptoms, noting any potential triggers or patterns. This information can be valuable for your healthcare provider.
  3. Stress Management: Since stress seems to worsen your symptoms, consider stress-reduction techniques such as meditation, yoga, or counseling.
  4. Avoid Known Allergens: Continue to avoid latex and be mindful of other potential allergens in your environment.

What you should look out for

Seek medical attention if you experience:

  • Difficulty breathing or swelling of the face, lips, or tongue
  • New or worsening symptoms
  • Any signs of infection, such as fever or redness around the rash

Remember, this information is not a substitute for professional medical advice. Please consult a healthcare provider for a formal diagnosis and treatment plan.

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2 mo ago


People Also Ask


What is chronic urticaria and how is it treated?

Chronic urticaria, also known as chronic hives, is a condition characterized by persistent itchy welts on the skin that last for six weeks or more. Treatment often involves antihistamines to reduce itching and swelling, and in some cases, other medications like corticosteroids or immunosuppressants may be prescribed by a doctor.


Could my symptoms be related to an autoimmune condition like lupus?

Given your family history of lupus, it's possible that an autoimmune condition could be contributing to your symptoms. Autoimmune conditions can cause skin rashes and other systemic symptoms. It's important to consult a healthcare provider for appropriate testing, which may include blood tests to check for autoimmune markers.


Why might stress exacerbate my skin rash and what can I do about it?

Stress can trigger or worsen skin conditions like rashes due to the body's release of stress hormones, which can affect the immune system and skin barrier. Managing stress through techniques such as meditation, yoga, or counseling can help reduce the impact of stress on your symptoms.


What should I do if over-the-counter medications like Benadryl are not relieving my symptoms?

If over-the-counter medications like Benadryl are not providing relief, it's important to consult a healthcare provider. They may recommend stronger antihistamines, corticosteroids, or other treatments. Additionally, they can help identify any underlying causes or triggers for your symptoms.


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