[30F] With recurring rashes, mouth sores, joint pain, and fatigue

Patient Description

A 30-year-old female reports recurring skin rashes on the arms, face, and chest for almost daily over the last 5 weeks. The rashes are itchy, bumpy, and pink, lasting about 12 hours before new ones appear. Benadryl capsules and calamine lotion help with itching but do not prevent new rashes. The patient also experiences painful mouth sores, mostly on the tongue and roof of the mouth, appearing twice in the last 5 weeks and lasting 5 to 7 days. Severe daily fatigue requires rest, and there is a dull, constant ache in the hips and ankles, rated 5 out of 10 in severity. The patient has lost 20 pounds over the last 3 months while counting calories and has experienced very low-grade fevers. No sensitivity to sunlight or lymph node swelling reported. Medical history includes chronic kidney stones, stage one chronic kidney disease, hypertension, endometriosis, and degenerative disc disease. Allergies to cephalosporins and the erythromycin family are noted. Current medications include a daily multivitamin, vitamin D, and vitamin B12 supplements, with occasional Tylenol for joint pain.

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Arora's Assessment

What might be happening

Based on your symptoms, here are some possible explanations:

  • Autoimmune Condition (e.g., Lupus): Your symptoms, including rashes, joint pain, mouth sores, and fatigue, could suggest an autoimmune condition like lupus. These conditions can cause the immune system to attack healthy tissues, leading to inflammation and various symptoms.

    • Typical Testing: Blood tests, including ANA and other specific markers, can help diagnose autoimmune conditions.
    • Treatment: Often involves medications to reduce inflammation and manage symptoms.
  • Fibromyalgia: This condition is characterized by widespread pain, fatigue, and other symptoms. It can sometimes be associated with other conditions like autoimmune diseases.

    • Treatment: Focuses on pain management, lifestyle changes, and sometimes medications.
  • Nutritional Deficiencies: Fatigue and mouth sores can sometimes be linked to deficiencies in vitamins like B12 or D.

    • Treatment: Supplementation and dietary adjustments.

What you can do

  1. Consult a Healthcare Provider: It's important to see a doctor for a thorough evaluation and appropriate testing.
  2. Symptom Tracking: Use MDandMe to journal your symptoms, track progress, and share insights with your provider.
  3. Manage Stress: Stress can exacerbate symptoms, so consider relaxation techniques like meditation or yoga.
  4. Stay Hydrated and Nourished: Ensure you're eating a balanced diet and staying hydrated to support overall health.

What you should look out for

  • Worsening Symptoms: If your symptoms become more severe or new symptoms appear, seek medical attention.
  • High Fever or Severe Pain: These could indicate a more serious issue requiring prompt care.
  • Unexplained Weight Loss: Continue monitoring your weight and discuss any concerns with your doctor.

Remember, this information is not a substitute for professional medical advice. Please consult a healthcare provider for a formal diagnosis and treatment plan.

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3 mo ago

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People Also Ask


What could be causing recurring skin rashes and mouth sores?

Recurring skin rashes and mouth sores can be caused by autoimmune conditions such as lupus, where the immune system mistakenly attacks healthy tissues, leading to inflammation and various symptoms.


How can autoimmune conditions like lupus be diagnosed?

Autoimmune conditions like lupus can be diagnosed through blood tests, including the antinuclear antibody (ANA) test and other specific markers that indicate the presence of autoimmune activity.


What are some common treatments for fibromyalgia?

Common treatments for fibromyalgia include pain management strategies, lifestyle changes such as regular exercise and stress reduction, and sometimes medications like antidepressants or anticonvulsants to help manage symptoms.


Can nutritional deficiencies cause symptoms like fatigue and mouth sores?

Yes, nutritional deficiencies, particularly in vitamins like B12 and D, can lead to symptoms such as fatigue and mouth sores. Supplementation and dietary adjustments can help address these deficiencies.


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