[25F] With persistent abdominal pain, gastrointestinal symptoms, and weight loss

Patient Description

A 25-year-old female presents with persistent abdominal pain for the past 4-5 months. The pain varies in nature, sometimes feeling sharp, crampy, or burning, and can occur in different areas of the lower abdomen. These episodes happen multiple times a day and can last from 30 minutes to several hours. The pain can be severe enough to curl the patient into a ball, although this has only happened twice. The patient has a history of constipation, which has recently become more severe, leading to hospital visits. Laxatives have not been very effective. The patient has noticed blood in her stool, which has been more concerning recently due to the larger amount and lack of pain. She experiences excessive gas, which has somewhat improved but is still present daily or every other day. The patient feels lightheaded, especially when bending over or standing up, sometimes to the point where she can't see and her tongue goes numb. This feeling can last for a few minutes and makes her feel unstable. She has been losing weight despite trying to eat more, losing 4 pounds in 8 days. The patient has noticed white mucus in her stool and has experienced bowel urgency, feeling like she needs to poop all the time. She also reports back pain and recent nausea. The patient has a family history of diabetes, cancer, and mental health issues. She is not currently taking any medications.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Inflammatory Bowel Disease (IBD): This includes conditions like Crohn's disease and ulcerative colitis. These conditions can cause chronic inflammation of the gastrointestinal tract, leading to symptoms like abdominal pain, diarrhea, blood in the stool, weight loss, and fatigue. The presence of white mucus in your stool and the severity of your symptoms suggest that this could be a possibility.

    • Typical treatments: Treatment often involves medications to reduce inflammation and manage symptoms, such as corticosteroids, immunosuppressants, and biologics. In some cases, surgery may be necessary. Diagnostic tests like colonoscopy, blood tests, and imaging studies are usually required to confirm the diagnosis.
  • Irritable Bowel Syndrome (IBS): This is a common disorder that affects the large intestine and can cause symptoms like cramping, abdominal pain, bloating, gas, and changes in bowel habits. While IBS does not cause blood in the stool or weight loss, it can coexist with other conditions.

    • Typical treatments: Treatment focuses on managing symptoms through dietary changes, stress management, and medications to relieve specific symptoms like pain or diarrhea.
  • Colorectal Cancer: Given your family history of cancer and the presence of blood in your stool, this is a possibility that should be ruled out. Colorectal cancer can cause symptoms like changes in bowel habits, blood in the stool, abdominal pain, and unexplained weight loss.

    • Typical treatments: Treatment may involve surgery, chemotherapy, radiation therapy, or targeted therapy. Early detection through screening tests like colonoscopy is crucial for effective treatment.
  • Iron Deficiency Anemia: Your symptoms of dizziness, fatigue, and low iron levels suggest that you might have iron deficiency anemia. This condition can be caused by chronic blood loss (such as from the gastrointestinal tract) and can lead to symptoms like lightheadedness, fatigue, and pale skin.

    • Typical treatments: Treatment involves addressing the underlying cause of the blood loss and taking iron supplements to replenish iron levels. Dietary changes to include more iron-rich foods can also help.

What you can do

  1. Consult a doctor: It is crucial to see a healthcare professional for a formal assessment and diagnosis. They can order relevant tests, such as blood work, stool tests, and imaging studies, to determine the cause of your symptoms.
  2. Keep a symptom journal: Use MDandMe to journal your symptoms, track your progress, and share longitudinal medical notes with your provider. This can help your doctor understand the pattern and severity of your symptoms.
  3. Stay hydrated and eat a balanced diet: Ensure you are drinking enough water and eating a nutritious diet rich in fiber to help manage your bowel movements. Avoid foods that seem to trigger your symptoms.
  4. Monitor your weight: Keep track of your weight and report any significant changes to your doctor.
  5. Rest and manage stress: Try to get enough rest and find ways to manage stress, as stress can exacerbate gastrointestinal symptoms.

What you should look out for

Seek medical attention more urgently if you experience any of the following:

  • Severe abdominal pain that does not go away
  • Persistent or worsening blood in your stool
  • Unexplained weight loss despite eating adequately
  • Severe dizziness or lightheadedness, especially if you feel like you might faint
  • Fever or signs of infection

Remember, while I can provide information and suggestions, I am not a doctor. It is important to consult with a healthcare professional to receive a formal diagnosis and appropriate treatment.

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4 mo ago


People Also Ask


What are the common symptoms of Inflammatory Bowel Disease (IBD)?

Common symptoms of Inflammatory Bowel Disease (IBD) include chronic abdominal pain, diarrhea, blood in the stool, weight loss, fatigue, and the presence of mucus in the stool. These symptoms result from chronic inflammation of the gastrointestinal tract.


How is Irritable Bowel Syndrome (IBS) different from Inflammatory Bowel Disease (IBD)?

Irritable Bowel Syndrome (IBS) is a functional disorder affecting the large intestine, characterized by symptoms like cramping, abdominal pain, bloating, gas, and changes in bowel habits. Unlike IBD, IBS does not cause inflammation, blood in the stool, or weight loss, although it can coexist with other conditions.


What are the potential causes of blood in the stool?

Blood in the stool can be caused by various conditions, including hemorrhoids, anal fissures, colorectal cancer, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), and gastrointestinal infections. It is important to consult a healthcare professional for an accurate diagnosis.


What lifestyle changes can help manage symptoms of gastrointestinal disorders?

Lifestyle changes that can help manage symptoms of gastrointestinal disorders include maintaining a balanced diet rich in fiber, staying hydrated, avoiding trigger foods, managing stress through relaxation techniques, and keeping a symptom journal to track patterns and triggers. Regular exercise and adequate rest are also beneficial.


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