[63F] Experiencing progressive muscle weakness

Patient Description

A 63-year-old female presents with a year-long history of progressive muscle weakness, predominantly in the upper arms, which has recently worsened. This weakness is constant and does not change with rest or activity. The patient also reports a persistent heavy feeling in the arms and has been unable to perform tasks such as pouring from a coffee pot without using both hands. Additionally, the patient experiences fatigue and mild depression. There is no difficulty swallowing, no change in voice, no shortness of breath, no eyelid drooping, and no double vision. The patient's medical history includes eczema diagnosed three years ago and a past occurrence of kidney stones. Current medications include RINVOQ and Prozac, and the patient has a known allergy to sulfa drugs. No other significant medical history or medication use was reported.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible causes for your symptoms could include:

  • Polymyositis: This is an inflammatory muscle disease that causes decreased mobility and muscle weakness. It's often associated with autoimmune conditions, which you mentioned you have. It usually affects the muscles closest to the trunk or torso. A common symptom is muscle weakness that gets worse over time.

    • Treatment typically involves medication to decrease inflammation and suppress the immune system.
  • Dermatomyositis: This is similar to polymyositis but also involves a skin rash, which could possibly be related to your eczema. However, you didn't mention a rash, so this may be less likely.

    • Treatment is similar to polymyositis and may also include treatment for the rash.
  • Medication side effects: Some medications, including RINVOQ, can cause muscle weakness. However, this would typically not be limited to the upper arms.

    • Treatment would involve discussing these side effects with your doctor, who may adjust your medication regimen.
  • Depression: Depression can cause physical symptoms such as fatigue and muscle weakness, as well as emotional symptoms such as feelings of sadness.

    • Treatment typically involves a combination of medication and therapy.

What you can do

  1. Consult your doctor: Given the severity and duration of your symptoms, it's important to consult with your healthcare provider. They can conduct a physical examination and possibly order tests such as blood tests or a muscle biopsy to help determine the cause of your muscle weakness.

  2. Monitor your symptoms: Keep track of your symptoms and any changes. This can help your healthcare provider in diagnosing and treating your condition.

  3. Stay active: Regular, gentle exercise can help maintain muscle strength and reduce fatigue.

  4. Eat a balanced diet: Proper nutrition can help your body heal and function properly.

What you should look out for

Seek immediate medical attention if you experience:

  • Difficulty swallowing or breathing
  • Rapid progression of muscle weakness
  • Severe pain
  • Fever or other signs of infection

Please remember that while I strive to provide accurate information, I'm not a doctor and this advice should not replace a consultation with a healthcare provider.

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11 mo ago

People Also Ask


What are the common symptoms of polymyositis?

Common symptoms of polymyositis include progressive muscle weakness, especially in muscles closest to the trunk, difficulty climbing stairs, lifting objects, or reaching overhead, and sometimes muscle pain. It can also be associated with fatigue and difficulty swallowing.


Can medications like RINVOQ cause muscle weakness?

Yes, medications like RINVOQ, which is used to treat autoimmune conditions, can sometimes cause muscle weakness as a side effect. However, this side effect is usually not limited to specific areas like the upper arms.


How can depression contribute to physical symptoms like muscle weakness?

Depression can lead to physical symptoms such as fatigue and muscle weakness due to changes in brain chemistry that affect energy levels and muscle function. It can also lead to decreased physical activity, which can contribute to muscle weakness.


What are the treatment options for muscle weakness caused by autoimmune conditions?

Treatment options for muscle weakness caused by autoimmune conditions like polymyositis typically include medications to reduce inflammation and suppress the immune system, such as corticosteroids or immunosuppressants. Physical therapy and exercise are also important to maintain muscle strength and function.


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