[56F] With persistent painful lower leg bruise and knot post-injury

Patient Description

A 56-year-old female presents with a painful bruise on her lower leg that has persisted for two weeks after being kicked. The bruise has turned a deep reddish color and is accompanied by a large knot and two large blood blisters. The pain is sharp, and the patient cannot rub or manipulate the area. The knot is firm and feels very hot. The patient has also noticed some itching around the bruise but no drainage or discharge from the blood blisters. There has been no fever, chills, numbness, or tingling in the lower leg or foot, and no difficulty moving the leg or foot, although there is significant pain around the leg. The patient has pre-existing swelling in the feet and ankles, so it is unclear if there is additional swelling. The patient has COPD, diagnosed 35 years ago, and is allergic to Tylenol. Current medications include blood pressure medications, Hydroxyzine 25 mg three times daily, Prozac 25 mg once daily, Wellbutrin 300 mg daily, iron and vitamin D supplements, pregabalin, and Hydroxyzine 50 mg for restless leg syndrome.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your symptoms:

Bruise, Knot, and Blood Blisters

  • Hematoma: The large knot and deep reddish color of the bruise suggest a hematoma, which is a collection of blood outside of blood vessels. This can occur after a significant impact, such as being kicked.
  • Infection: The heat and redness around the area could indicate an infection, especially since the pain is sharp and persistent. Infections can develop in areas of trauma and may require medical treatment.
  • Compartment Syndrome: Although less common, the severe pain and firmness of the knot could indicate compartment syndrome, a condition where increased pressure within a muscle compartment reduces blood flow, potentially leading to muscle and nerve damage.

Typical Treatments and Testing

  • Hematoma: Treatment usually involves rest, ice, compression, and elevation (RICE). Over-the-counter pain relievers like ibuprofen can help manage pain and inflammation.
  • Infection: If an infection is suspected, a healthcare provider may prescribe antibiotics. They may also perform blood tests or imaging studies to assess the extent of the infection.
  • Compartment Syndrome: This is a medical emergency. If suspected, immediate medical evaluation is necessary, and treatment may involve surgical intervention to relieve pressure.

What you can do

For the Bruise, Knot, and Blood Blisters

  1. Rest and Elevate: Keep your leg elevated as much as possible to reduce swelling.
  2. Ice: Apply an ice pack to the area for 15-20 minutes every 2-3 hours to help reduce pain and swelling.
  3. Avoid Popping Blisters: Do not pop the blood blisters, as this can increase the risk of infection.
  4. Pain Management: Take over-the-counter pain relievers like ibuprofen (Advil) to help manage pain and inflammation, but avoid Tylenol due to your allergy.
  5. Monitor for Infection: Keep an eye on the area for signs of infection, such as increased redness, warmth, swelling, or pus. If you notice any of these signs, seek medical attention promptly.

For General Health

  • Symptom Tracking: Use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.
  • Consult a Healthcare Provider: Given the severity and persistence of your symptoms, it's important to consult a healthcare provider for a thorough evaluation and appropriate treatment.

What you should look out for

Given the severity of your symptoms and the possibility of serious conditions, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Increased Pain or Swelling: If the pain or swelling worsens significantly.
  • Signs of Infection: Such as increased redness, warmth, swelling, or pus.
  • Numbness or Tingling: In your lower leg or foot.
  • Difficulty Moving Your Leg or Foot: If you start having trouble moving your leg or foot.

Remember, while I can provide information and suggestions, I am not a doctor. It's important to seek care from real health professionals to receive a formal diagnosis and treatment if appropriate. If you have more questions or need further assistance, feel free to continue the conversation.

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People Also Ask


What is a hematoma and how is it treated?

A hematoma is a collection of blood outside of blood vessels, often caused by an injury. It can cause swelling, pain, and discoloration. Treatment typically involves rest, ice, compression, and elevation (RICE) to reduce swelling and pain. Over-the-counter pain relievers like ibuprofen can also help.


How can I tell if a bruise is infected?

Signs of an infected bruise include increased redness, warmth, swelling, sharp pain, and the presence of pus. If you notice these symptoms, it's important to seek medical attention as you may need antibiotics.


What is compartment syndrome and why is it serious?

Compartment syndrome is a condition where increased pressure within a muscle compartment reduces blood flow, potentially leading to muscle and nerve damage. It is serious because it can cause permanent damage if not treated promptly, often requiring surgical intervention to relieve the pressure.


What are the risks of popping blood blisters?

Popping blood blisters can increase the risk of infection, as it creates an open wound that can be exposed to bacteria. It's best to leave them intact and monitor for signs of infection, such as increased redness or pus.


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