[50M] With night sweats and sore throat

Patient Description

A 50-year-old male presents with night sweats that have been occurring for one week, soaking through his clothes. He also reports a sore throat and has noticed lumps or swollen areas in his neck. The patient has experienced fever and fatigue recently but denies any recent weight loss. There is a family history of cancer or infectious diseases. The patient is up to date with vaccinations, including the flu shot and COVID-19 vaccine. He has no pre-existing conditions, chronic illnesses, or known allergies to medications. He is not currently taking any medications, including over-the-counter medications, supplements, or herbal remedies, and has not recently stopped taking any medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

  1. Infection:

    • Bacterial or Viral Infection: Night sweats, sore throat, fever, and fatigue can be symptoms of an infection. Common infections include the flu, mononucleosis, or a bacterial throat infection. Since you are already on Amoxicillin, it suggests that a bacterial infection might have been suspected.
    • Tuberculosis (TB): Although less common, TB can cause night sweats, fever, and fatigue. It is more likely if you have been in contact with someone with TB or have traveled to areas where TB is common.
  2. Lymphoma:

    • Hodgkin's or Non-Hodgkin's Lymphoma: These types of cancers can cause night sweats, fever, fatigue, and swollen lymph nodes in the neck. This is a serious condition that requires prompt medical attention.
  3. Hyperthyroidism:

    • Overactive Thyroid: This condition can cause night sweats, fatigue, and other symptoms like weight loss and increased heart rate. However, you did not report weight loss, which makes this less likely.

What you can do

Night Sweats and Fever:

  • See a Doctor: Given the severity and persistence of your symptoms, it is important to see a healthcare provider as soon as possible. They may perform blood tests, imaging studies, or other diagnostic tests to determine the cause.
  • Stay Hydrated: Drink plenty of fluids to stay hydrated, especially if you are sweating a lot.
  • Keep Cool: Use lightweight bedding and keep your bedroom cool to help manage night sweats.

Sore Throat:

  • Continue Medication: Continue taking Amoxicillin as prescribed by your doctor. Do not stop taking it without consulting your healthcare provider.
  • Gargle with Salt Water: This can help soothe a sore throat. Mix 1/4 to 1/2 teaspoon of salt in a glass of warm water and gargle several times a day.
  • Stay Hydrated: Drink plenty of fluids to keep your throat moist and to help your body fight the infection.

Fatigue:

  • Rest: Ensure you get plenty of rest to help your body recover.
  • Balanced Diet: Eat a balanced diet rich in fruits, vegetables, and lean proteins to support your immune system.

Swollen Lymph Nodes:

  • Monitor: Keep an eye on the swollen lymph nodes. If they continue to grow or become more painful, seek medical attention.

What you should look out for

Given the severity of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Difficulty Breathing: If you experience shortness of breath or difficulty breathing, seek emergency medical attention.
  • Severe Pain: If you experience severe pain in your throat, neck, or elsewhere, seek medical attention.
  • High Fever: If your fever is very high (above 103°F or 39.4°C) or persistent, seek medical attention.
  • Unexplained Weight Loss: If you start to lose weight without trying, seek medical attention.

Remember, while I can provide information and suggestions, I am not a doctor. It is important to consult with a healthcare professional for a formal diagnosis and appropriate treatment. You can also use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

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6 mo ago

People Also Ask


What are common causes of night sweats in adults?

Common causes of night sweats in adults include infections (such as tuberculosis or the flu), hormonal imbalances (like hyperthyroidism), certain medications, and more serious conditions like lymphoma. It's important to consult a healthcare provider for a proper diagnosis.


How can swollen lymph nodes in the neck be evaluated?

Swollen lymph nodes in the neck can be evaluated through a physical examination, blood tests, imaging studies like ultrasound or CT scans, and sometimes a biopsy to determine the underlying cause.


What are the symptoms of lymphoma that one should be aware of?

Symptoms of lymphoma can include persistent night sweats, unexplained fever, fatigue, swollen lymph nodes (especially in the neck, armpits, or groin), and unexplained weight loss. If these symptoms are present, it's important to seek medical evaluation.


How can one differentiate between a viral and bacterial throat infection?

A viral throat infection often presents with symptoms like a sore throat, runny nose, and cough, and usually resolves on its own. A bacterial throat infection, such as strep throat, may cause more severe symptoms like a high fever, swollen lymph nodes, and white patches on the tonsils, and often requires antibiotic treatment.


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