[45F] Experiencing nocturnal anxiety, panic attacks, and various physical symptoms

Patient Description

A 45-year-old female reports suffering from anxiety and panic attacks at night for the past 2 years, which often begin with heart palpitations, body tensing, shaking, and uncontrollable yawning. These episodes occur at bedtime when lying down. The patient has also developed a 'moon face' with reddish cheeks over the last 6 months, accompanied by sudden weight gain, high blood pressure, and sore joints, particularly in the ankles, feet, and wrists, which are painful especially in the morning. The joint pain has been present for a year and is rated as a 4 out of 10 in severity. The patient mentions that the joint soreness correlates with drops in estrogen levels. No prior history of anxiety was reported, and no specific triggers other than palpitations were identified. The patient has not found any techniques or activities that alleviate the anxiety. No recent injuries or accidents have been reported that could account for the joint soreness.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Cushing's Syndrome: This condition is caused by an excess of cortisol, a hormone produced by your adrenal glands. Symptoms can include weight gain, particularly around the midsection and upper back, fatigue, rounded face (moon face), high blood pressure, and anxiety.

    • Diagnosis typically involves a physical exam, lab tests to measure cortisol levels, and imaging tests. Treatment usually involves lowering cortisol levels through surgery, radiation, medications, or reducing the use of corticosteroid medications.
  • Panic Disorder: This is a type of anxiety disorder characterized by recurrent and unexpected panic attacks. Symptoms can include palpitations, shaking, and a sense of impending doom, typically occurring at night.

    • Diagnosis is usually made based on a clinical evaluation. Treatment can involve cognitive behavioral therapy (CBT), medications, and lifestyle changes.
  • Hyperthyroidism: This condition is caused by an overactive thyroid gland, leading to an excess of thyroid hormone. Symptoms can include anxiety, palpitations, weight loss, and joint pain.

    • Diagnosis typically involves a physical exam, lab tests to measure thyroid hormone levels, and imaging tests. Treatment usually involves medications, radioactive iodine, or surgery.

What you can do

  1. Consult a healthcare professional: It's important to discuss your symptoms with a healthcare provider. They can provide a formal diagnosis and appropriate treatment options.

  2. Lifestyle modifications: Regular exercise, a balanced diet, and adequate sleep can help manage symptoms of anxiety and joint pain. Avoid caffeine and alcohol, which can trigger panic attacks and increase anxiety.

  3. Mindfulness and relaxation techniques: Techniques such as deep breathing, yoga, and meditation can help manage anxiety and panic attacks.

What you should look out for

  1. Worsening of symptoms: If your symptoms worsen or if you develop new symptoms, seek medical attention immediately.

  2. Severe panic attacks: If your panic attacks become more frequent or severe, seek medical help immediately.

  3. Signs of a serious condition: If you experience severe headache, vision problems, or severe abdominal pain, seek emergency medical care. These could be signs of a serious condition, such as a pituitary tumor, which can be associated with Cushing's syndrome.

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care.

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1 yr ago

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People Also Ask


What are the common symptoms of Cushing's Syndrome?

Common symptoms of Cushing's Syndrome include weight gain, particularly around the midsection and upper back, a rounded face (moon face), high blood pressure, fatigue, and anxiety. It is caused by an excess of cortisol in the body.


How can panic attacks be managed or treated?

Panic attacks can be managed through cognitive behavioral therapy (CBT), medications such as antidepressants or anti-anxiety drugs, and lifestyle changes. Techniques like deep breathing, mindfulness, and avoiding triggers such as caffeine can also help.


What lifestyle changes can help reduce anxiety and joint pain?

Lifestyle changes that can help reduce anxiety and joint pain include regular exercise, maintaining a balanced diet, ensuring adequate sleep, and practicing relaxation techniques like yoga and meditation. Avoiding caffeine and alcohol can also be beneficial.


What are the potential causes of a 'moon face' and sudden weight gain?

A 'moon face' and sudden weight gain can be caused by conditions like Cushing's Syndrome, which involves excess cortisol production. Other potential causes include certain medications, such as corticosteroids, and hormonal imbalances.


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