[44F] Experiencing fatigue, muscle weakness, and sensory disturbances

What might be happening

Based on the symptoms you've described, there are a couple of possible explanations:

1. Multiple Sclerosis (MS): This is a condition where the immune system attacks the protective covering of nerves. It can cause symptoms like fatigue, muscle weakness, balance issues, numbness, and vision problems. The presence of gray matter changes on your MRI and the variety of symptoms you've experienced over the years could be consistent with MS. It's important to follow up with a neurologist for further evaluation and testing.

2. Peripheral Neuropathy: This involves damage to the nerves outside the brain and spinal cord, which can cause weakness, numbness, and pain, usually in the hands and feet. It can also affect other areas of the body and lead to balance issues.

Given the complexity and progression of your symptoms, I strongly recommend seeing a healthcare professional, particularly a neurologist, for a comprehensive evaluation. They can provide a more accurate diagnosis and discuss potential treatment options to help manage your symptoms.

What you can do

Fatigue and Leg Stumbling:

• Consult a Neurologist: It's important to get a thorough evaluation to determine the underlying cause of your symptoms. A neurologist can help with this.
• Rest and Manage Stress: Ensure you get adequate rest and try stress-reducing techniques like meditation or gentle yoga, which might help alleviate some symptoms.
• Track Symptoms: Use MDandMe to journal your symptoms, track progress, and share insights with your healthcare provider. This can help in understanding patterns and triggers.

Numbness and Vision Issues:

• Protect Affected Areas: Be cautious with areas that are numb to avoid injury, as you might not feel pain as usual.
• Manage Vision Changes: When experiencing blurry vision, rest your eyes and avoid bright lights. Consider seeing an eye specialist if this persists.

Urinary Urgency:

• Pelvic Floor Exercises: These can help strengthen the muscles that control urination. Consider consulting a physical therapist who specializes in pelvic health.
• Plan Bathroom Breaks: Try to use the restroom regularly to avoid sudden urgency.

What you should look out for

Given the severity of your symptoms and the possibility of life-impacting conditions, you should seek medical care as soon as you can. Reasons to seek care even more urgently include:

• Sudden severe headache or vision loss
• Severe weakness or numbness, especially on one side of the body
• Difficulty speaking or understanding speech
• Loss of bladder or bowel control

These symptoms could indicate a serious condition that requires immediate medical attention. Please prioritize your health and consult with a healthcare professional to get the care you need.