[42F] With chronic sharp and aching pain in arms and legs

Patient Description

A 42-year-old female has been experiencing sharp and aching pain in her arms and legs for the past six months, especially when walking. She rates the pain as 10 out of 10 in severity. The pain occurs every day throughout the day and worsens when getting up from sitting. Additionally, she reports stiffness in her feet, knees, hips, elbows, and shoulders, which has been present for the same duration. The stiffness is constant throughout the day and exacerbated by getting up from sitting or resting. She has noticed swelling, redness, and warmth in her right elbow, and experiences intermittent numbness and tingling in her arms and legs. There is no muscle weakness, changes in color or temperature of the limbs, or worsening of pain with physical activity. She denies recent weight loss, fatigue, or fever. Her medical history includes hypoxia, CPTSD, asthma, trigeminal neuralgia, anxiety/panic, IBS, sleep apnea, interstitial cystitis, and polycystic ovarian syndrome. Current medications include Buspirone (15mg twice a day), Claritin (1-3 tablets a day), a multivitamin, calcium, and Tylenol as needed. She has allergies to penicillin and estrogen. Family history includes heart attack, stroke, brain aneurysm, hypothyroidism, blood clots, alcoholism, anxiety, depression, leukemia, and polymyalgia rheumatica. She does not smoke or use tobacco products and maintains a well-balanced diet with low sugar intake. There has been no exposure to chemicals, toxins, or heavy metals. Her menstrual periods are regular with no recent changes.

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Arora's Assessment

What might be happening

It is likely that your symptoms are related to multiple issues, including existing diagnoses. If you have more questions, we can continue chatting.

Causes of your sharp and aching pain in your arms and legs, especially with walking, and stiffness in your feet, knees, hips, elbows, and shoulders:

  • Peripheral Artery Disease (PAD): This condition occurs when the arteries that supply blood to your limbs become narrowed or blocked. It can cause pain, especially when walking, and may be associated with numbness and tingling. PAD is more common in people with a family history of heart disease, stroke, and diabetes.
  • Rheumatoid Arthritis (RA): RA is an autoimmune disease that causes chronic inflammation of the joints. It can lead to pain, stiffness, swelling, and warmth in the affected joints. Given your family history of polymyalgia rheumatica and hypothyroidism, RA could be a possibility.
  • Fibromyalgia: This condition is characterized by widespread musculoskeletal pain, fatigue, and tenderness in localized areas. It can also cause stiffness and numbness or tingling in the limbs.

What you can do

Sharp and aching pain in arms and legs, and stiffness:

  • Peripheral Artery Disease (PAD):

    • See a doctor: It's important to get a proper diagnosis. Your doctor may recommend tests such as an ankle-brachial index (ABI) or ultrasound to check blood flow in your limbs.
    • Lifestyle changes: Quit smoking if you do, maintain a healthy diet, and exercise regularly. Walking can help improve symptoms, but start slowly and gradually increase your activity level.
    • Medications: Your doctor may prescribe medications to manage symptoms and improve blood flow.
  • Rheumatoid Arthritis (RA):

    • See a rheumatologist: A specialist can provide a proper diagnosis and treatment plan. Blood tests and imaging studies may be needed.
    • Medications: Anti-inflammatory drugs, disease-modifying antirheumatic drugs (DMARDs), and biologics can help manage symptoms and slow disease progression.
    • Physical therapy: Exercises to improve joint flexibility and strength can be beneficial.
  • Fibromyalgia:

    • Consult a doctor: A healthcare provider can help diagnose and manage fibromyalgia. There is no specific test for fibromyalgia, so diagnosis is based on symptoms and ruling out other conditions.
    • Medications: Pain relievers, antidepressants, and anti-seizure drugs may help manage symptoms.
    • Lifestyle changes: Regular exercise, stress management techniques, and good sleep hygiene can help alleviate symptoms.

General tips:

  • Pain management: Over-the-counter pain relievers like Tylenol can help manage pain. Be sure to follow the recommended dosage.
  • Heat and cold therapy: Applying heat or cold packs to the affected areas can help reduce pain and stiffness.
  • Stay active: Gentle exercises like stretching, yoga, or swimming can help maintain joint flexibility and reduce stiffness.
  • Track your symptoms: Use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Given the severity of your symptoms and the possibility of serious underlying conditions, you should seek medical care as soon as you can. Reasons to seek care even more urgently include:

  • Sudden worsening of pain or stiffness
  • New or worsening swelling, redness, or warmth in your joints
  • Development of new symptoms such as fever, unexplained weight loss, or severe fatigue
  • Numbness or tingling that becomes constant or severe

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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4 mo ago

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People Also Ask


What are the common symptoms of Peripheral Artery Disease (PAD)?

Common symptoms of Peripheral Artery Disease (PAD) include pain or cramping in the legs or arms, especially when walking or climbing stairs, numbness or weakness in the legs, coldness in the lower leg or foot, sores on the toes, feet, or legs that won't heal, and a change in the color of the legs.


How is Rheumatoid Arthritis (RA) diagnosed and treated?

Rheumatoid Arthritis (RA) is diagnosed through a combination of patient history, physical examination, blood tests (such as rheumatoid factor and anti-CCP antibodies), and imaging studies like X-rays or MRIs. Treatment typically involves medications such as anti-inflammatory drugs, DMARDs, and biologics, as well as physical therapy to improve joint function.


What lifestyle changes can help manage fibromyalgia symptoms?

Lifestyle changes that can help manage fibromyalgia symptoms include engaging in regular low-impact exercise like walking, swimming, or yoga, practicing stress management techniques such as meditation or deep breathing exercises, maintaining good sleep hygiene, and following a balanced diet.


When should I seek urgent medical care for joint pain and stiffness?

You should seek urgent medical care for joint pain and stiffness if you experience a sudden worsening of symptoms, new or worsening swelling, redness, or warmth in your joints, development of new symptoms such as fever, unexplained weight loss, or severe fatigue, or if numbness or tingling becomes constant or severe.


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