[35F] With chronic pain, fatigue, and neurological symptoms

Patient Description

A 35-year-old female has been experiencing a range of symptoms over the past year. The primary concern is a deep, dull aching pain on the entire right side of her body, including the upper arm, leg, hip, elbow, and knee. This pain has been present for about 6 months, occurs multiple times a day, and lasts for a couple of hours each time. The pain came on gradually and does not change in intensity. There are no specific triggers or injuries that might explain this pain. The joint pain is described as sharp and rated 5 out of 10 in severity. Additionally, she reports feeling exhausted and experiencing brain fog for the past year, which has affected her daily routine. She also has dull and achy bone pain in her upper arm and femur down to her shin, which comes and goes, and a sense of fullness under her right rib for about 8 months. An MRI revealed a bony island and sclerosis lesions on her spine, but her physician is not concerned. She has a small liver hemangioma, which her doctor also isn't worried about. She experiences a burning sensation over the skin of her back on and off for about 8 months, occasional slight numbness in her right leg, and muscle weakness in her right side. She has no history of autoimmune diseases, neurological conditions, or other chronic illnesses, except for a past infection with Epstein-Barr virus as a teenager, which is currently not active. She has a family history of lupus (aunt). She does not use tobacco, alcohol, or recreational drugs, and her diet includes sufficient vitamins and minerals. There have been no recent exposures to toxins or travel to new locations.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential diagnoses that could explain your condition. Here are some possibilities:

1. Chronic Pain Syndrome

  • Rationale: Chronic pain syndrome can cause persistent pain that lasts for months or even years. It can affect various parts of the body, including the spine, joints, and muscles. The pain can be dull, aching, or sharp and may come and go.
  • Typical Treatments: Treatment often includes a combination of medications (such as pain relievers, antidepressants, or anticonvulsants), physical therapy, and lifestyle changes. Cognitive-behavioral therapy (CBT) can also be helpful in managing chronic pain.

2. Fibromyalgia

  • Rationale: Fibromyalgia is a condition characterized by widespread musculoskeletal pain, fatigue, and cognitive difficulties (often referred to as "fibro fog"). It can also cause tenderness in specific areas of the body.
  • Typical Treatments: Treatment may include medications (such as pain relievers, antidepressants, or anticonvulsants), physical therapy, exercise, and stress management techniques.

3. Autoimmune Disease

  • Rationale: Given your family history of lupus and your symptoms of joint pain, muscle weakness, and fatigue, an autoimmune disease could be a possibility. Autoimmune diseases can cause a wide range of symptoms and may affect multiple systems in the body.
  • Typical Treatments: Treatment depends on the specific autoimmune disease but may include medications to reduce inflammation and suppress the immune system, as well as lifestyle changes and physical therapy.

4. Bone or Joint Disorders

  • Rationale: Conditions such as osteoarthritis or other degenerative joint diseases could cause the joint and bone pain you're experiencing. These conditions can cause pain, stiffness, and swelling in the affected joints.
  • Typical Treatments: Treatment may include pain relievers, anti-inflammatory medications, physical therapy, and lifestyle changes. In some cases, surgical interventions may be necessary.

What you can do

Pain Management

  • Consult a Doctor: Given the severity and persistence of your pain, it's important to consult a healthcare professional for a thorough evaluation and appropriate treatment plan.
  • At Home: You can try over-the-counter pain relievers like ibuprofen or acetaminophen, apply heat or cold packs to the affected areas, and engage in gentle stretching exercises to help alleviate pain.

Fatigue and Brain Fog

  • Consult a Doctor: Discuss your symptoms of fatigue and brain fog with your healthcare provider to rule out any underlying conditions and receive appropriate treatment.
  • At Home: Ensure you get adequate rest, maintain a balanced diet, and engage in regular physical activity. Keeping a symptom journal using MDandMe can help track your symptoms and identify any potential triggers.

Joint and Muscle Weakness

  • Consult a Doctor: A healthcare professional can evaluate your joint and muscle weakness and recommend appropriate treatments, such as physical therapy or medications.
  • At Home: Engage in low-impact exercises, such as swimming or walking, to help strengthen your muscles and improve joint function. Avoid activities that exacerbate your pain.

Burning Sensation

  • Consult a Doctor: Discuss the burning sensation with your healthcare provider to determine the underlying cause and receive appropriate treatment.
  • At Home: Avoid tight clothing and apply soothing lotions or creams to the affected area to help alleviate the burning sensation.

What you should look out for

Given the complexity and persistence of your symptoms, it's important to seek medical care to receive a formal diagnosis and appropriate treatment. Reasons to seek care more urgently include:

  • Worsening Pain: If your pain becomes more severe or unmanageable.
  • New Symptoms: If you develop new symptoms, such as swelling, redness, or warmth in the affected areas.
  • Neurological Symptoms: If you experience new or worsening numbness, tingling, or muscle weakness.
  • Systemic Symptoms: If you develop unexplained fevers, significant weight loss, or other systemic symptoms.

Remember, while I can provide information and suggestions, it's important to consult with a real healthcare professional to receive a formal diagnosis and treatment plan. You can use MDandMe to journal your symptoms, track your progress, get insights, and share longitudinal medical notes with your provider.

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4 mo ago


People Also Ask


What could be causing the deep, dull aching pain on one side of my body?

The deep, dull aching pain on one side of your body could be due to conditions like chronic pain syndrome or fibromyalgia. These conditions can cause persistent pain that affects various parts of the body. It's important to consult a healthcare professional for a thorough evaluation.


How can I manage the fatigue and brain fog I am experiencing?

To manage fatigue and brain fog, ensure you get adequate rest, maintain a balanced diet, and engage in regular physical activity. Keeping a symptom journal can help track your symptoms and identify potential triggers. Consulting a healthcare provider is also recommended to rule out underlying conditions.


Is there a connection between my symptoms and a possible autoimmune disease?

Given your family history of lupus and symptoms like joint pain, muscle weakness, and fatigue, there could be a connection to an autoimmune disease. It's important to discuss these symptoms with a healthcare provider for proper evaluation and diagnosis.


What are the potential treatments for the burning sensation on my skin?

For the burning sensation on your skin, avoid tight clothing and apply soothing lotions or creams to the affected area. It's important to discuss this symptom with your healthcare provider to determine the underlying cause and receive appropriate treatment.


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