[40F] With severe acid reflux and nocturnal symptoms

Patient Description

A 40-year-old female has been experiencing severe acid reflux for an extended period. Symptoms primarily occur at night, especially after eating and lying down. Triggers include citrus and sugar, with the latter causing phlegm production. The patient reports nocturnal coughing spells with blood in the phlegm and occasional random chest pain. Regurgitation and a sour taste in the mouth are also noted. The patient is currently taking Pantoprazole 40mg daily, Famotidine, aloe vera drinks, and vitamin supplements (potassium and magnesium). She has a history of asthma since age 9 and an allergy to Flagyl. The patient does not smoke or consume alcohol, and there is no family history of gastrointestinal issues or acid reflux.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

  • Gastroesophageal Reflux Disease (GERD): This is a chronic condition where stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). This backwash (acid reflux) can irritate the lining of your esophagus. Your symptoms of severe acid reflux, especially at night, and regurgitation are common in GERD. The presence of blood in your phlegm could indicate irritation or damage to the esophagus, which can occur with severe or prolonged reflux.

    • Typical treatments include lifestyle changes, medications like proton pump inhibitors (Pantoprazole) or H2 blockers (Famotidine), and in some cases, surgery.
  • Laryngopharyngeal Reflux (LPR): Sometimes called "silent reflux," LPR can cause symptoms like coughing, throat clearing, and phlegm production without the typical heartburn. It can also lead to irritation and bleeding in the throat, which might explain the blood in your phlegm.

    • Treatment is similar to GERD, focusing on dietary changes and medications to reduce acid production.
  • Asthma-related Symptoms: Your history of asthma could be contributing to your symptoms. Acid reflux can exacerbate asthma symptoms, and asthma can sometimes cause coughing and phlegm production.

    • Managing both asthma and reflux effectively can help alleviate symptoms.

What you can do

  1. Dietary Adjustments: Avoid foods and drinks that trigger your symptoms, such as citrus and sugar. Eating smaller, more frequent meals and avoiding eating right before lying down can also help.

  2. Lifestyle Changes: Elevate the head of your bed to prevent nighttime symptoms. Avoid tight clothing that can put pressure on your abdomen.

  3. Medication Management: Continue taking your prescribed medications as directed. Discuss with your healthcare provider if adjustments are needed.

  4. Symptom Tracking: Use MDandMe to journal your symptoms, track your progress, and identify any patterns or triggers. This information can be valuable for your healthcare provider.

What you should look out for

  • Seek Medical Attention If:
    • You continue to see blood in your phlegm or if it worsens.
    • You experience severe chest pain, as this could indicate a more serious condition.
    • Your symptoms do not improve with treatment or lifestyle changes.

Remember, while this information can be helpful, it's important to consult with a healthcare professional for a formal diagnosis and personalized treatment plan.

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2 mo ago

People Also Ask


What are the common triggers for acid reflux and how can they be avoided?

Common triggers for acid reflux include spicy foods, citrus, chocolate, caffeine, alcohol, and fatty foods. To avoid these triggers, try to identify which specific foods or drinks cause your symptoms and limit or eliminate them from your diet. Eating smaller meals and avoiding eating close to bedtime can also help.


How can GERD lead to blood in phlegm and what should be done if this occurs?

GERD can cause irritation or damage to the esophagus, leading to bleeding and blood in phlegm. If you notice blood in your phlegm, it's important to seek medical attention to rule out any serious conditions. Treatment may involve medications to reduce acid production and lifestyle changes to minimize reflux.


What lifestyle changes can help manage nighttime acid reflux symptoms?

To manage nighttime acid reflux, elevate the head of your bed by 6-8 inches to prevent acid from flowing back into the esophagus. Avoid eating 2-3 hours before lying down, and wear loose-fitting clothing to reduce abdominal pressure. These changes can help reduce nighttime symptoms.


How does asthma interact with acid reflux and what can be done to manage both conditions?

Asthma and acid reflux can exacerbate each other. Acid reflux can trigger asthma symptoms, while asthma can lead to increased coughing and phlegm production. Managing both conditions involves taking prescribed medications, avoiding triggers, and possibly using a humidifier to keep airways moist. Consult with a healthcare provider for a tailored management plan.


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