[40F] With multiple chronic symptoms and surgical history

Patient Description

A 40-year-old female presents with a complex medical history including hypothyroidism diagnosed 6 years ago, elevated fasting glucose, a complete hysterectomy and oophorectomy, cholecystectomy, and IBS-like symptoms for the past 10 years. The patient reports difficulty losing weight despite efforts with exercise and diet, noting the best results with a low carb diet but difficulty maintaining it due to low energy. Hair thinning has been a concern for 10-15 years, affecting the entire scalp. The patient experiences dry eyes, with inadequate oil production leading to occasional blocked tear ducts, a condition present for over 10 years and managed with treatments to open the glands. Acne has been a persistent issue since puberty, with sporadic occurrences of large, painful pimples on the face and body. The patient is unable to take hormone replacements for the oophorectomy and is currently on Levothyroxine for hypothyroidism and Lexapro. Additionally, the patient has a latex allergy and sensitivity to medications that can aggravate stomach issues, causing nausea and pain.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible conditions that could explain your symptoms:

  • Hypothyroidism: This condition, which you've been diagnosed with, can cause a number of the symptoms you've described, including difficulty losing weight, thinning hair, and dry skin. Hypothyroidism is a condition in which your thyroid gland doesn't produce enough of certain crucial hormones.

    • Treatment typically involves daily use of the synthetic thyroid hormone levothyroxine, which you're currently taking.
  • Polycystic ovary syndrome (PCOS): Although you've had a hysterectomy and oophorectomy, if these symptoms were present before those procedures, PCOS could be a possibility. PCOS is a hormonal disorder common among women of reproductive age and can cause difficulty losing weight, acne, and thinning hair.

    • Treatment of PCOS typically involves lifestyle changes and medication to manage symptoms and prevent complications.
  • Dry eye syndrome: This condition occurs when your tears aren't able to provide adequate lubrication for your eyes, which can result in the dryness and blockage of tear ducts you've described.

    • Treatment can involve lifestyle changes, over-the-counter eyedrops or ointments, or prescription eye drops or ointments, or tear-stimulating drugs.
  • Insulin resistance or prediabetes: Your elevated fasting glucose levels could be a sign of these conditions, which can make it harder to lose weight.

    • Treatment typically involves lifestyle changes such as diet and exercise, and sometimes medication.

Please note that these are possibilities based on the information you've provided, and not a definitive diagnosis. It's important to consult with a healthcare professional who can evaluate your symptoms and medical history in person.

What you can do

Here are some general suggestions that might help with your symptoms:

  1. Continue taking your prescribed medication and follow up with your doctor regularly to manage your hypothyroidism.
  2. Maintain a healthy diet and regular exercise routine. Even if weight loss is slow, these habits are beneficial for overall health.
  3. For dry eyes, consider using over-the-counter artificial tear solutions. If you're already doing this and it's not helping, consult with your doctor or a specialist.
  4. Keep your skin clean and use non-irritating skin products. It might be helpful to consult with a dermatologist for your acne.
  5. Monitor your blood glucose levels and follow up with your doctor. They might recommend lifestyle changes or medication to manage your glucose levels.

What you should look out for

Please seek immediate medical attention if you experience any of the following:

  • Severe abdominal pain
  • Severe headache
  • Any signs of infection, such as fever, chills, or unexplained weight loss
  • Symptoms of a thyroid crisis, such as a rapid heartbeat, high fever, or delirium.

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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1 yr ago

People Also Ask


How does hypothyroidism affect weight loss and hair thinning?

Hypothyroidism can slow down metabolism, making it difficult to lose weight. It can also lead to hair thinning due to reduced hormone production affecting hair growth cycles. Treatment typically involves taking levothyroxine to normalize hormone levels.


What are the common symptoms and treatments for dry eye syndrome?

Dry eye syndrome occurs when tears do not provide adequate lubrication. Symptoms include dryness, irritation, and blocked tear ducts. Treatments include artificial tears, prescription eye drops, and lifestyle changes to manage symptoms.


How can elevated fasting glucose levels indicate insulin resistance or prediabetes?

Elevated fasting glucose levels can indicate insulin resistance or prediabetes, where the body's cells do not respond effectively to insulin. This can lead to higher blood sugar levels and difficulty losing weight. Management includes lifestyle changes like diet and exercise, and sometimes medication.


What are the potential causes and treatments for persistent acne in adults?

Persistent acne in adults can be caused by hormonal imbalances, stress, or skin care products. Treatments include topical or oral medications, lifestyle changes, and consulting a dermatologist for personalized care.


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