[32F] With multiple systemic symptoms and a complex medical history

Patient Description

A 32-year-old female presents with a constellation of symptoms including fatigue, muscle weakness, joint pain, irregular periods, hirsutism, hair loss, hearing loss, gastrointestinal issues, swollen lymph nodes, neuropathy, sleep disturbances, significant weight gain, brain fog, memory loss, periods of severe pain with low blood pressure, acid reflux, skin pigment changes, easy bruising, pain upon skin pressure, tachycardia, dissociative experiences, and left facial muscle problems. Symptoms such as fatigue, muscle pain, and weakness, facial muscle problems, neuropathy, weight gain, and gastrointestinal issues are particularly bothersome. The patient has experienced a sudden and substantial weight gain over a short period, irregular menses for the past 5 months, and a moderate increase in facial hair. The patient's medical history includes eosinophilic asthma diagnosed in 2020 and eosinophilic granulomatosis with polyangiitis (EGPA) diagnosed in 2021. She is currently on a regimen of Dulera, Methotrexate, Nucala, Wellbutrin, Cymbalta, Pepcid, and Zyrtec, with no recent changes in medication or noted side effects. The patient has allergies to lidocaine and sulfa drugs. Her mother has a history of Hashimoto's thyroiditis, suggesting a potential familial predisposition to autoimmune conditions.

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Arora's Assessment

What might be happening

Based on the information you have provided, possible unifying diagnoses include:

  • Polycystic Ovary Syndrome (PCOS): This is a hormonal disorder common among women of reproductive age. Symptoms can include irregular periods, excess hair growth (hirsutism), weight gain, and difficulty with weight loss. It can also cause fatigue and sleep problems.

    • Treatment of PCOS often involves lifestyle changes such as diet and exercise, as well as medications to manage symptoms.
  • Hypothyroidism: This is a condition in which your thyroid gland doesn't produce enough of certain crucial hormones. Symptoms can include fatigue, weight gain, joint and muscle pain, and hair loss. Hashimoto's disease, an autoimmune disorder, is the most common cause of hypothyroidism.

    • Treatment typically involves daily use of the synthetic thyroid hormone levothyroxine.
  • Fibromyalgia: This is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. Symptoms sometimes begin after a physical trauma, surgery, infection or significant psychological stress.

    • Treatment often involves a combination of medications, exercise, stress-management measures, and healthy lifestyle habits.

Please note that these are potential diagnoses and it's important to consult with a healthcare provider for a formal diagnosis.

What you can do

  1. Schedule an appointment with your healthcare provider to discuss your symptoms. They may want to perform some tests to help determine a diagnosis.
  2. Keep a symptom diary. This can help you and your healthcare provider identify patterns and triggers for your symptoms.
  3. Try to maintain a healthy lifestyle. This includes regular exercise, a balanced diet, and adequate sleep. These can help manage symptoms of many conditions, including PCOS, hypothyroidism, and fibromyalgia.

What you should look out for

Reasons to seek immediate medical attention:

  • If you experience severe pain or discomfort
  • If your symptoms significantly interfere with your daily activities
  • If you notice any new or worsening symptoms

Remember, while I strive to provide accurate information, I'm an AI and not a substitute for professional medical advice. Always consult with a healthcare provider for a formal diagnosis and treatment options.

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1 yr ago

Top picked over-the-counter products for Painful Periods (Dysmenorrhea)

People Also Ask


What are the common symptoms of Polycystic Ovary Syndrome (PCOS)?

Common symptoms of PCOS include irregular periods, excess hair growth (hirsutism), weight gain, difficulty losing weight, fatigue, and sleep problems. It can also cause acne and thinning hair on the scalp.


How is hypothyroidism diagnosed and treated?

Hypothyroidism is typically diagnosed through blood tests that measure levels of thyroid hormones and thyroid-stimulating hormone (TSH). Treatment usually involves daily use of synthetic thyroid hormone levothyroxine to normalize hormone levels.


What lifestyle changes can help manage fibromyalgia symptoms?

Lifestyle changes that can help manage fibromyalgia symptoms include regular exercise, stress management techniques, maintaining a balanced diet, and ensuring adequate sleep. These measures can help reduce pain and improve overall well-being.


What should I do if I experience severe pain or discomfort with my symptoms?

If you experience severe pain or discomfort, it's important to seek immediate medical attention. This is especially crucial if your symptoms significantly interfere with daily activities or if you notice any new or worsening symptoms.


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