[38M] With sudden onset hematuria

Patient Description

A 38-year-old male presents with sudden onset of blood in the urine noticed this morning around 7 AM. The patient reports no associated pain or discomfort and has not experienced this symptom before. There is no history of recent trauma, strenuous exercise, urinary tract infections, or kidney issues. The patient denies any changes in the color or smell of urine, fever, chills, recent weight loss, night sweats, swelling in the legs or ankles, or changes in urinary habits. The patient recently started taking doxycycline a little over a week ago and has not experienced any side effects from it. The patient has also made significant changes to his diet, specifically not eating as much. There is no known exposure to chemicals or toxins, and no recent travel. The patient has a history of Type-2 Diabetes diagnosed about a year ago and has no known family history of kidney disease, bladder cancer, or other urinary tract issues. The patient has allergies to Amoxicillin, Levaquin, Singular, and Benadryl. Current medications include Lisinopril 40MG once a day, Metformin 500MG twice a day, Amlodipine 1.5MG once a day, Abilify 2MG once a day, Hydrochlorothiazide 12.5MG once a day, and Cymbalta 60MG once a day.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for the blood in your urine:

  • Urinary Tract Infection (UTI): Although you don't have pain or discomfort, UTIs can sometimes present with blood in the urine without other symptoms. UTIs are more common in people with diabetes.

    • Treatment: Typically involves antibiotics prescribed by a healthcare provider. A urine test can confirm the diagnosis.
  • Kidney Stones: These can cause blood in the urine without pain, especially if the stone is small and not causing a blockage.

    • Treatment: May include increased fluid intake, pain management, and sometimes medical procedures to remove the stones. Imaging tests like an ultrasound or CT scan can help diagnose kidney stones.
  • Medication Side Effects: Doxycycline and other medications can sometimes cause blood in the urine as a side effect.

    • Treatment: Consult your healthcare provider to discuss the possibility of switching medications.
  • Diabetes-Related Kidney Issues: Diabetes can affect the kidneys and lead to conditions like diabetic nephropathy, which can cause blood in the urine.

    • Treatment: Managing blood sugar levels and possibly medications to protect kidney function. Blood and urine tests can help assess kidney function.
  • Bladder or Kidney Infections: These can sometimes present without pain but still cause blood in the urine.

    • Treatment: Typically involves antibiotics. A urine culture can help identify the specific bacteria causing the infection.

What you can do

While it's important to consult a healthcare provider for a formal diagnosis and treatment, here are some steps you can take in the meantime:

  1. Stay Hydrated: Drink plenty of water to help flush out your urinary system.
  2. Monitor Symptoms: Keep track of any additional symptoms that may develop, such as pain, fever, or changes in urinary habits.
  3. Avoid Strenuous Activities: Until you have a clearer understanding of the cause, avoid activities that could exacerbate the issue.
  4. Medication Review: Consult your healthcare provider about the possibility of doxycycline or other medications causing this symptom.
  5. Use MDandMe: Journal your symptoms, track your progress, and share your medical notes with your healthcare provider for a more comprehensive evaluation.

What you should look out for

Seek medical attention more urgently if you experience any of the following:

  • Severe Pain: Especially in your back or sides, which could indicate kidney stones or a more serious condition.
  • Fever or Chills: These could indicate an infection that needs prompt treatment.
  • Increased Blood in Urine: If the amount of blood increases or if you see clots.
  • Difficulty Urinating: Any changes in your ability to urinate, such as increased frequency, urgency, or pain.

Remember, while this information can help guide you, it's crucial to consult a healthcare provider for a formal diagnosis and appropriate treatment.

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4 mo ago

People Also Ask


Can blood in the urine occur without any pain or discomfort?

Yes, blood in the urine can occur without pain or discomfort. Conditions like kidney stones, certain infections, or even some medications can cause this symptom without accompanying pain.


Could my medications be causing blood in my urine?

Yes, some medications, including antibiotics like doxycycline, can cause blood in the urine as a side effect. It's important to discuss any new symptoms with your healthcare provider to determine if a medication change is necessary.


How does diabetes affect the kidneys and potentially cause blood in the urine?

Diabetes can lead to kidney damage over time, a condition known as diabetic nephropathy. This can cause blood in the urine as the kidneys become less effective at filtering waste from the blood.


What are the potential causes of blood in the urine if there is no history of trauma or infection?

Blood in the urine without a history of trauma or infection can be caused by several factors, including kidney stones, medication side effects, or underlying conditions like diabetes-related kidney issues. It's important to consult a healthcare provider for a proper diagnosis.


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