[38F] Experiencing severe night sweats, weight loss, and lymph node swelling

What might be happening

Based on the information you've provided, the following conditions could be possible:

• Lymphoma: This is a type of cancer that starts in the cells that are part of the body's immune system. The symptoms you've described such as night sweats, unintentional weight loss, swollen lymph nodes, and fatigue are common in lymphoma. Your family history of lymphoma also increases your risk.

  • Diagnostic tests for lymphoma usually include blood tests, imaging tests, and a biopsy of a swollen lymph node.
  • Treatment typically involves chemotherapy, radiation therapy, and in some cases, stem cell transplant.

• Autoimmune diseases (such as Lupus or Sjogren's syndrome): These are conditions where the immune system mistakenly attacks the body's own cells. Your previous diagnoses and the use of hydroxychloroquine (a medication commonly used to treat autoimmune diseases) suggest this possibility. Symptoms can include fatigue, hair loss, and dry skin.

  • Diagnosis usually involves blood tests, and treatment typically involves managing symptoms and preventing flare-ups.

• Infections: Certain infections can cause symptoms like night sweats, swollen lymph nodes, and fatigue. Given your low lymphocyte count, this could be a possibility.

  • Diagnosis usually involves identifying the pathogen through blood tests or cultures, and treatment typically involves antibiotics or antiviral medications.

• Anemia: This is a condition where you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues. This could explain your fatigue and dizziness upon standing.

  • Diagnosis usually involves blood tests, and treatment depends on the cause of the anemia.

What you can do

Given the severity and duration of your symptoms, it's important that you seek medical attention as soon as possible. Here are some steps you can take:

1. Schedule an appointment with your primary care provider. They can perform an initial evaluation and refer you to a specialist if necessary.
2. Write down all your symptoms, including when they started, how often they occur, and any patterns you've noticed.
3. Make a list of all the medications and supplements you're currently taking, as well as any known allergies or adverse reactions you have.
4. Be prepared to discuss your personal and family medical history.

What you should look out for

Please seek immediate medical attention if you experience any of the following:

• Severe chest pain or shortness of breath
• High fever (temperature over 100.4°F)
• Severe abdominal pain
• Confusion, slurred speech, or difficulty moving one side of your body
• Any other symptom that is severe or concerning to you

Please remember that while I strive to provide accurate information, I am not a doctor and this advice should not replace a consultation with a healthcare professional.