[38F] Experiencing fatigue and swollen lymph nodes

Patient Description

A 38-year-old female presents with persistent fatigue over the last month and the recent appearance of a tender swollen lymph node under her jaw, noticed a week ago. Another swollen lymph node on her neck, present for a month, appears to be decreasing in size. Both nodes are approximately the size of the tip of her index finger. The patient reports no significant weight changes, difficulty swallowing, breathing difficulties, night sweats, or fevers. Appetite may be slightly decreased due to fatigue. Past medical history includes asthma, pre-eclampsia, and gestational diabetes, but currently, there are no chronic illnesses. The patient had COVID-19 last month. She is taking vitamin D, calcium, and a birth control pill, with no known drug allergies. No other medications are reported.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your symptoms:

  • Post-viral Syndrome: After a viral infection, such as COVID-19, some people experience lingering symptoms. This can include fatigue and swollen lymph nodes. The fact that your lymph node is tender and you're feeling tired could be a sign of your body still recovering from the virus.

    • Treatment typically involves rest, maintaining a healthy diet, and staying hydrated.
  • Mononucleosis: This is a viral infection that can cause fatigue, fever, and swollen lymph nodes. It's often caused by the Epstein-Barr virus.

    • Treatment usually involves rest, hydration, and over-the-counter remedies for pain and fever.
  • Other Viral or Bacterial Infections: Many different types of infections can cause swollen lymph nodes and fatigue. These include common conditions like strep throat, measles, ear infections, an infected (abscessed) tooth, or HIV.

    • Treatment depends on the specific infection. Antibiotics are used for bacterial infections, while viral infections often just need time and supportive care.
  • Lymphoma: This is a type of cancer that starts in the cells of the body's immune system, including the lymph nodes. It can cause swollen lymph nodes, fatigue, and other symptoms. However, it's less likely given your age and the fact that your lymph nodes are tender (which is less common in lymphoma).

    • Treatment typically involves chemotherapy, radiation therapy, and other cancer treatments.

Please remember, these are just possibilities and not a definitive diagnosis. It's important to consult with a healthcare provider who can evaluate your symptoms and medical history in person.

What you can do

  1. Continue to monitor your symptoms. If they persist or worsen, seek medical attention.
  2. Maintain a healthy lifestyle. This includes eating a balanced diet, getting regular exercise, staying hydrated, and getting plenty of sleep.
  3. Over-the-counter pain relievers can help with discomfort from swollen lymph nodes.

What you should look out for

Seek immediate medical attention if you experience:

  • Severe fatigue that prevents you from doing your daily activities
  • High fever (over 100.4°F)
  • Difficulty breathing or swallowing
  • Night sweats
  • Unexplained weight loss

Remember, while I strive to provide accurate information, I'm not a doctor and this advice should not replace a consultation with a healthcare provider.

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11 mo ago

People Also Ask


What are the common causes of swollen lymph nodes and fatigue after a viral infection?

Common causes of swollen lymph nodes and fatigue after a viral infection include the body's immune response to the virus, which can cause inflammation and swelling in the lymph nodes. Fatigue is also a common symptom as the body recovers from the infection.


How can I differentiate between post-viral syndrome and other conditions like mononucleosis?

Post-viral syndrome often involves lingering symptoms like fatigue and swollen lymph nodes after a viral infection, whereas mononucleosis typically presents with additional symptoms such as fever, sore throat, and more pronounced fatigue. A healthcare provider can perform specific tests to diagnose mononucleosis.


When should I be concerned about swollen lymph nodes and seek medical attention?

You should seek medical attention if you experience severe fatigue that interferes with daily activities, high fever, difficulty breathing or swallowing, night sweats, or unexplained weight loss, as these could indicate a more serious condition.


What lifestyle changes can help alleviate symptoms of fatigue and swollen lymph nodes?

To alleviate symptoms, maintain a healthy lifestyle by eating a balanced diet, staying hydrated, getting regular exercise, and ensuring adequate sleep. Over-the-counter pain relievers can also help manage discomfort from swollen lymph nodes.


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