[34F] Experiencing random body jerks with depression and stress

Patient Description

A 34-year-old female has been experiencing random body jerks affecting various parts of her body, including her arms and legs, over the past week. These jerks are severe and not limited to just muscle spasms. The patient reports feeling very depressed and stressed, with a racing mind, which has been ongoing for over a month. She also experiences trouble sleeping and a loss of appetite. The patient has a history of schizophrenia, diagnosed at age 10, and PTSD, diagnosed at age 19, along with Stockholm syndrome and abandonment issues. She is currently on medications including Effexor 75 mg once daily, propranolol 2 mg as needed, trazodone 100 mg at bedtime, citalopram, and Wellbutrin, with no recent changes in dosage. The patient consumes a small amount of caffeine daily and has not been exposed to any new environments or substances recently. There is no history of recent injury or physical strain.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential explanations for what you might be experiencing:

  1. Medication Side Effects: The combination of medications you're taking, particularly those affecting the central nervous system like Effexor, trazodone, citalopram, and Wellbutrin, can sometimes lead to side effects such as muscle jerks or spasms. It's important to discuss these symptoms with your healthcare provider to determine if your medications might be contributing to your symptoms.

  2. Stress and Anxiety: High levels of stress and anxiety can sometimes manifest physically, leading to symptoms like muscle jerks or twitches. Given your recent increase in stress and depression, this could be a contributing factor.

  3. Neurological Causes: While less likely, it's important to consider that neurological conditions can sometimes cause involuntary movements. If your symptoms persist or worsen, a neurological evaluation might be necessary.

What you can do

Random Body Jerks:

  • Consult Your Doctor: It's important to discuss these new symptoms with your healthcare provider, especially given your current medication regimen. They may need to adjust your medications or explore other causes.
  • Track Symptoms: Use MDandMe to journal your symptoms, noting when they occur, their severity, and any potential triggers. This information can be valuable for your healthcare provider.

Stress and Depression:

  • Seek Support: Consider reaching out to a mental health professional for support in managing your stress and depression. Therapy can be a helpful tool in addressing these issues.
  • Practice Relaxation Techniques: Techniques such as deep breathing, meditation, or yoga can help reduce stress and may alleviate some of your symptoms.

What you should look out for

  • Worsening Symptoms: If your jerking movements become more frequent or severe, or if you experience new symptoms such as weakness, numbness, or changes in vision, seek medical attention promptly.
  • Mental Health Changes: If you notice a significant change in your mental health, such as increased depression or anxiety, or if you have thoughts of self-harm, it's important to seek help immediately.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and treatment plan.

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1 mo ago

People Also Ask


Can medications cause random body jerks or spasms?

Yes, certain medications, especially those affecting the central nervous system, can cause side effects such as muscle jerks or spasms. It's important to discuss any new or worsening symptoms with your healthcare provider to determine if your medications might be contributing.


How can stress and anxiety lead to physical symptoms like muscle jerks?

High levels of stress and anxiety can manifest physically in various ways, including muscle jerks or twitches. This is because stress can lead to increased muscle tension and nervous system activity, which may result in involuntary movements.


What are some potential neurological causes of involuntary movements?

Neurological causes of involuntary movements can include conditions such as epilepsy, movement disorders like Parkinson's disease, or other neurological issues. If symptoms persist or worsen, a neurological evaluation may be necessary to rule out these conditions.


What steps can I take to manage stress and depression effectively?

To manage stress and depression, consider seeking support from a mental health professional, practicing relaxation techniques like deep breathing or meditation, and maintaining a healthy lifestyle with regular exercise and a balanced diet. These strategies can help reduce stress and improve overall mental health.


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