[23F] With breast lump and systemic symptoms

Patient Description

A 23-year-old female presents with a large, hard, and tender lump in the right breast, persisting for over seven months. The patient reports associated symptoms of fatigue, weight loss, loss of appetite, and dimpling of the skin over the lump. There is no history of recent breast injury, and no diagnostic imaging has been performed yet. The patient denies any nipple discharge. Family history is significant for colon cancer. The patient's menstrual cycle occasionally varies, being one to three days late, and sometimes up to a week late, with no known pregnancies. The patient has a history of asthma diagnosed at age 11 and is not currently on any medications. There are no known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Breast Lump: The presence of a hard, tender lump in your breast that has been there for several months, along with changes in the skin and nipple discharge, warrants further evaluation. While breast lumps can be caused by benign conditions such as cysts or fibroadenomas, it is important to rule out breast cancer, especially given the changes in the skin and discharge. Breast cancer can sometimes present with a hard lump, skin dimpling, and nipple changes.

    • Typical evaluation for a breast lump includes imaging tests such as a mammogram or ultrasound, and sometimes a biopsy to determine the nature of the lump.
  • Fatigue and Weight Loss: These symptoms, along with loss of appetite, can be associated with a variety of conditions, including hormonal imbalances, chronic infections, or more serious conditions like cancer. Given your family history of colon cancer, it is important to discuss these symptoms with a healthcare provider.

What you can do

  1. Consult a Healthcare Provider: It is important to see a doctor as soon as possible for a thorough evaluation of the breast lump and associated symptoms. They may recommend imaging tests and possibly a biopsy to determine the cause of the lump.

  2. Monitor Symptoms: Keep track of any changes in the lump, skin, or nipple discharge. Note any new symptoms or changes in your overall health.

  3. Use MDandMe: Consider using the MDandMe app to journal your symptoms, track any changes, and share this information with your healthcare provider. This can help in monitoring your condition and providing valuable information during medical consultations.

What you should look out for

  • Seek Immediate Medical Attention: If you notice any rapid changes in the lump, such as increased size or pain, or if you experience new symptoms like difficulty breathing or severe fatigue, seek medical attention promptly.

  • Follow-Up on Family History: Given your family history of colon cancer, discuss with your healthcare provider whether any additional screenings or genetic counseling might be appropriate for you.

Remember, while I can provide information and suggestions, it is important to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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People Also Ask


What could cause a hard, tender lump in the breast that persists for several months?

A hard, tender lump in the breast that persists for several months could be caused by benign conditions such as cysts or fibroadenomas, but it is important to rule out breast cancer, especially if there are changes in the skin or nipple. A healthcare provider should evaluate the lump to determine its nature.


How are fatigue and weight loss related to breast lumps or other conditions?

Fatigue and weight loss can be associated with a variety of conditions, including hormonal imbalances, chronic infections, or more serious conditions like cancer. These symptoms, along with a breast lump, should be discussed with a healthcare provider to determine the underlying cause.


What diagnostic tests are typically recommended for evaluating a breast lump?

Typical diagnostic tests for evaluating a breast lump include imaging tests such as a mammogram or ultrasound. In some cases, a biopsy may be performed to determine the nature of the lump and whether it is benign or malignant.


How does family history of cancer affect the risk of developing breast cancer?

A family history of cancer, such as colon cancer, can increase the risk of developing certain types of cancer, including breast cancer. It is important to discuss family history with a healthcare provider, who may recommend additional screenings or genetic counseling.


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