[22F] With swollen mole on vulva causing discomfort

Patient Description

A 22-year-old female reports a sudden swelling of a mole on her vulva, which has caused significant discomfort, itching, and irritation. The patient has not experienced any discharge or bleeding from the mole. There have been no recent changes in her menstrual cycle, hormonal changes, or travel that might explain the symptoms. She has not used any new personal care products or experienced any friction in the area. Her medical history includes Factor V Leiden, diagnosed approximately seven years ago, and rheumatoid arthritis, diagnosed this year. She is currently taking meloxicam, an anti-inflammatory medication, and has no known allergies or adverse reactions to medications.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for the sudden swelling and irritation of the mole on your vulva:

  • Irritated or Inflamed Mole: Sometimes, moles can become irritated due to friction, pressure, or minor trauma, leading to swelling and discomfort. This can happen even if you don't recall any specific incident.

    • Treatment typically involves avoiding further irritation and monitoring the mole for changes. If the irritation persists, a healthcare provider may recommend topical treatments to reduce inflammation.
  • Infection: Although you haven't noticed any discharge, it's possible for a mole to become infected, especially if there's been any unnoticed scratching or minor injury.

    • Treatment may involve topical or oral antibiotics if an infection is confirmed by a healthcare provider.
  • Dermatological Conditions: Conditions such as dermatitis or eczema can cause localized swelling and itching, potentially affecting moles.

    • Treatment often includes topical corticosteroids or other anti-inflammatory medications.

Given your medical history of rheumatoid arthritis, it's important to consider that systemic inflammation could potentially influence skin changes, although this is less likely to be the sole cause of a swollen mole.

What you can do

  1. Monitor the Mole: Keep an eye on the mole for any further changes in size, color, or shape. Take note of any new symptoms such as bleeding or discharge.
  2. Avoid Irritation: Try to minimize friction or pressure on the area. Wear loose-fitting clothing and avoid any products that might irritate the skin.
  3. Consult a Healthcare Provider: It's important to have any new or changing moles evaluated by a healthcare professional, especially if they cause discomfort or concern. They can provide a formal assessment and recommend appropriate treatment.
  4. Use MDandMe: Consider using the MDandMe app to journal your symptoms, track any changes, and share this information with your healthcare provider for a more comprehensive evaluation.

What you should look out for

Seek medical attention if you notice any of the following:

  • Rapid changes in the mole's appearance, such as significant growth or color change
  • Bleeding, oozing, or crusting of the mole
  • Persistent pain or discomfort that doesn't improve
  • Any signs of infection, such as increased redness, warmth, or pus

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and treatment plan.

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1 mo ago

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People Also Ask


What could cause a mole to suddenly swell and become irritated?

A mole can swell and become irritated due to factors like friction, pressure, or minor trauma. It can also be due to dermatological conditions such as dermatitis or eczema.


Can a mole become infected even if there is no discharge?

Yes, a mole can become infected without noticeable discharge. Infection might occur due to unnoticed scratching or minor injury, and it may require antibiotics if confirmed by a healthcare provider.


How can systemic inflammation from rheumatoid arthritis affect skin changes?

Systemic inflammation from rheumatoid arthritis can potentially influence skin changes, although it is less likely to be the sole cause of a swollen mole. It may contribute to overall skin sensitivity or inflammation.


What are the signs that a mole might need medical evaluation?

A mole should be evaluated by a healthcare professional if it shows rapid changes in size, color, or shape, starts bleeding, oozing, or crusting, causes persistent pain, or shows signs of infection like increased redness or warmth.


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