[36F] With a newly appeared mole on vulva

Patient Description

A 36-year-old female noticed a small mole or blood blister on her vulva about a week ago. It appeared suddenly and feels irritated and sore, especially after attempting to pop it, thinking it might be an ingrown hair. The mole has not changed in size, shape, or color over the past few days. There is no unusual discharge, odor, or bleeding from the area, but there is some itching after the attempt to pop it. The patient has a history of left fallopian tube removal following an ectopic pregnancy, a miscarriage, and experiences frequent UTIs after intercourse. She takes cranberry pills, vitamin B12 supplements, and Tylenol for a sore throat. She has chronic back and neck pain, for which she will start physical therapy soon. No known drug allergies. No prescription medications or birth control are currently being used.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for the mole or blood blister on your vulva:

  • Angiokeratoma: These are small, benign (non-cancerous) lesions that can appear as dark red to black spots on the skin, including the vulva. They can sometimes be mistaken for blood blisters and may become irritated or sore if touched or manipulated.

    • Treatment is usually not necessary unless they cause discomfort or cosmetic concern, in which case a healthcare provider can offer options such as laser therapy or surgical removal.
  • Vulvar Cyst: A blocked gland or hair follicle can lead to a cyst, which might appear suddenly and feel sore, especially if irritated.

    • Treatment may involve warm compresses to encourage drainage, but if it persists or becomes more painful, a healthcare provider might need to drain it.
  • Melanocytic Nevus (Mole): A new mole can appear on the vulva, just like any other part of the body. While most moles are benign, any new or changing mole should be evaluated by a healthcare provider to rule out skin cancer.

    • Monitoring for changes in size, shape, or color is important, and a healthcare provider may perform a biopsy if there are concerns.

What you can do

While it's important to consult a healthcare provider for a formal assessment, here are some steps you can take in the meantime:

  1. Avoid further irritation: Refrain from trying to pop or manipulate the lesion to prevent further irritation or infection.
  2. Keep the area clean and dry: Gently wash the area with mild soap and water, and pat dry.
  3. Monitor for changes: Keep an eye on the lesion for any changes in size, shape, or color, and take note of any new symptoms.
  4. Use MDandMe: Consider using the MDandMe app to journal your symptoms, track any changes, and share this information with your healthcare provider.

What you should look out for

Seek medical attention if you notice any of the following:

  • Rapid changes in the size, shape, or color of the lesion
  • Persistent or worsening pain, itching, or irritation
  • Any signs of infection, such as increased redness, swelling, or pus
  • If you develop any new symptoms that concern you

Remember, while this information can be helpful, it is not a substitute for professional medical advice. Please consult a healthcare provider for a thorough evaluation and appropriate management.

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1 mo ago

People Also Ask


What is an angiokeratoma and how is it treated?

An angiokeratoma is a small, benign lesion that appears as a dark red to black spot on the skin, including the vulva. Treatment is usually not necessary unless it causes discomfort or cosmetic concern, in which case options like laser therapy or surgical removal can be considered.


How can I differentiate between a vulvar cyst and a mole?

A vulvar cyst is often caused by a blocked gland or hair follicle and may feel sore, especially if irritated. A mole, or melanocytic nevus, is a pigmented spot that can appear anywhere on the body. Monitoring for changes in size, shape, or color can help differentiate them, and a healthcare provider can offer a definitive diagnosis.


What should I do if I notice a new mole on my vulva?

If you notice a new mole on your vulva, it's important to monitor it for any changes in size, shape, or color. Consulting a healthcare provider is recommended to rule out skin cancer, and they may perform a biopsy if there are concerns.


When should I seek medical attention for a lesion on my vulva?

You should seek medical attention if you notice rapid changes in the size, shape, or color of the lesion, persistent or worsening pain, itching, or irritation, signs of infection like increased redness, swelling, or pus, or if you develop any new symptoms that concern you.


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