[21F] With skin sensitivity, joint pain, and fatigue

Patient Description

A 21-year-old female reports experiencing sensitive skin that welts with minor scratches or pressure, and random burning sensations that are hot to the touch but do not itch. These burning episodes last 20-40 minutes and occur without specific triggers, though they are alleviated by cold water. The patient also reports joint pain occurring randomly, frequent peeling of the skin inside her cheeks, significant fatigue despite difficulty falling asleep, and sensitivity to sunlight, which causes hot blotches on her skin. She has a family history of lupus and thalassemia but has not been evaluated for autoimmune conditions due to financial constraints. Her medical history includes kidney stones, swelling around the right kidney, a hiatal hernia, and unspecified liver damage. She is allergic to milk, pine trees, and dust. The patient is not currently taking any medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential explanations:

  1. Dermatographia (Skin Writing): The welts you experience from minor scratches or pressure could be a condition known as dermatographia. This is a form of physical urticaria where the skin becomes raised and inflamed when scratched or rubbed. It's generally harmless but can be uncomfortable.

  2. Autoimmune Conditions: Given your family history of lupus and your symptoms of joint pain, fatigue, and skin sensitivity, it's possible that an autoimmune condition could be contributing to your symptoms. Lupus, for example, can cause joint pain, skin rashes, and fatigue. However, a formal diagnosis would require evaluation by a healthcare professional.

  3. Photosensitivity: Your sensitivity to sunlight and the resulting skin blotches could be a form of photosensitivity, which is sometimes associated with autoimmune conditions like lupus.

  4. Anisocoria and Light Sensitivity: Anisocoria, or unequal pupil sizes, can cause light sensitivity. This might be unrelated to your other symptoms but is worth mentioning to a healthcare provider.

Typical treatments for these conditions might include antihistamines for dermatographia, lifestyle modifications, and possibly medications to manage autoimmune conditions if diagnosed.

What you can do

For Skin Welts and Burning Sensations:

  • Avoid scratching or applying pressure to your skin when possible.
  • Use over-the-counter antihistamines to help reduce welts and discomfort.
  • Apply cool compresses to soothe burning sensations.

For Joint Pain and Fatigue:

  • Engage in gentle exercises like stretching or yoga to maintain joint flexibility.
  • Ensure you get adequate rest and maintain a regular sleep schedule.
  • Consider keeping a symptom journal using MDandMe to track your symptoms and identify any potential triggers.

For Photosensitivity:

  • Wear protective clothing and sunscreen when outdoors to minimize sun exposure.
  • Use sunglasses to protect your eyes from bright light.

What you should look out for

While your symptoms are not immediately life-threatening, it's important to monitor for any changes or worsening of symptoms. Seek medical attention if you experience:

  • Severe or persistent joint pain
  • New or worsening skin rashes
  • Significant changes in weight or energy levels
  • Any new symptoms that concern you

Given your family history and symptoms, it would be beneficial to consult with a healthcare provider when possible to explore the possibility of an autoimmune condition. They may recommend blood tests or other evaluations to help determine the cause of your symptoms. Remember, while I can provide information, a healthcare professional can offer a formal diagnosis and treatment plan.

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2 mo ago

People Also Ask


What is dermatographia and how is it treated?

Dermatographia, also known as skin writing, is a condition where the skin becomes raised and inflamed when scratched or rubbed. It is generally harmless but can be uncomfortable. Treatment often includes over-the-counter antihistamines to reduce symptoms and avoiding triggers like scratching or pressure on the skin.


How can I manage photosensitivity and protect my skin from sunlight?

To manage photosensitivity, it's important to minimize sun exposure by wearing protective clothing, using broad-spectrum sunscreen, and wearing sunglasses. Staying in the shade and avoiding peak sunlight hours can also help protect your skin.


What are common symptoms of lupus and how is it diagnosed?

Common symptoms of lupus include joint pain, skin rashes, fatigue, and photosensitivity. Diagnosis typically involves a combination of medical history, physical examination, and blood tests to check for specific antibodies. A healthcare provider can provide a formal diagnosis and recommend appropriate treatment.


What lifestyle changes can help alleviate joint pain and fatigue?

Lifestyle changes to alleviate joint pain and fatigue include engaging in gentle exercises like stretching or yoga to maintain joint flexibility, ensuring adequate rest and a regular sleep schedule, and maintaining a balanced diet. Keeping a symptom journal can also help identify potential triggers and patterns.


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