[69M] Experiencing persistent low-grade fever, night sweats, and shortness of breath

Patient Description

A 69-year-old male has been experiencing a constant daily low-grade fever of around 101°F for over three weeks, with episodes typically occurring at 2 PM, 10 PM, and sometimes at 4 AM. The fever only subsides with the use of Tylenol. Additionally, for the past five days, the patient has been waking up with night sweats severe enough to require changing clothes. The patient has lost 7-8 pounds in the past month and experiences shortness of breath during daily activities but reports no chest pain. The patient is a chronic smoker and has a dry cough, which he attributes to smoking. The patient's medical history includes an acute stroke in 2018 and a recent diagnosis of tuberculosis with elevated CRP and ESR levels two weeks ago. Current medications include Brilanta, Metformin, and Folic Acid. The patient has no known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Tuberculosis (TB): This is an infectious disease that primarily affects the lungs but can also affect other parts of the body. It's caused by the bacterium Mycobacterium tuberculosis. You mentioned that you tested positive for TB, which could explain your fever, night sweats, weight loss, and shortness of breath.

    • Treatment for TB usually involves taking several types of medications for a long period of time (6 to 9 months).
  • Infection or Inflammation: Your elevated CRP and ESR levels indicate that there may be inflammation or an infection in your body. This could be due to TB or another condition.

    • Treatment would depend on the specific cause of the inflammation or infection.
  • Chronic Obstructive Pulmonary Disease (COPD): This is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. It's most often caused by long-term exposure to irritating gases or particulate matter, most often from cigarette smoke. Your history of smoking and symptoms of shortness of breath and cough could be indicative of COPD.

    • Treatment for COPD can involve medications, oxygen therapy, pulmonary rehabilitation, or surgery in severe cases.

Please note that these are possible diagnoses based on the information you've provided, and only a healthcare professional can provide a definitive diagnosis.

What you can do

  1. It's important to follow your doctor's instructions for treating your TB. This usually involves taking several medications for a long period of time. It's crucial to take all of your medications as prescribed, even if you start to feel better. Not doing so can lead to drug-resistant TB.

  2. Try to quit smoking. This can help to slow the progression of COPD and other smoking-related health problems.

  3. Maintain a healthy diet to help support your immune system and prevent further weight loss.

  4. Try to get plenty of rest to help your body recover.

What you should look out for

You should seek immediate medical attention if you experience:

  • Severe difficulty breathing
  • Chest pain
  • Coughing up blood
  • A high fever that doesn't go away with medication
  • Any other severe or worsening symptoms

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care.

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1 yr ago

People Also Ask


What are the common symptoms of tuberculosis?

Common symptoms of tuberculosis include a persistent cough that lasts more than three weeks, chest pain, coughing up blood, fatigue, weight loss, fever, night sweats, and loss of appetite.


How does smoking affect conditions like COPD and tuberculosis?

Smoking can worsen respiratory conditions like COPD by causing further damage to the lungs and airways, leading to increased symptoms such as shortness of breath and cough. It can also impair the immune system, making it harder to fight infections like tuberculosis.


What is the significance of elevated CRP and ESR levels?

Elevated CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) levels are indicators of inflammation in the body. They can suggest the presence of an infection or an inflammatory condition, but they are not specific to any one disease.


Why is it important to complete the full course of TB medication?

Completing the full course of TB medication is crucial to ensure that all the bacteria are killed and to prevent the development of drug-resistant TB, which is much harder to treat and can lead to more severe health complications.


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