[58M] Experiencing cold sensation and numbness in right upper thigh

Patient Description

A 58-year-old male reports occasional episodes where his right upper thigh feels extremely cold, described as a stinging sensation, accompanied by numbness. During these episodes, which last approximately 30 minutes, the patient experiences a loss of sensation when touching the affected area. There are no alleviating factors identified. The patient's medical history is unremarkable with no known chronic illnesses or allergies. Current medications include Trazodone, Sertraline, Rasuvastatin, Adderall, Metoprolol, Tamsulosin, Vitamin B12, and Vitamin D. No other symptoms were reported.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are a few possible conditions:

  • Peripheral Neuropathy: This condition results from damage to the peripheral nerves, which often causes weakness, numbness, and pain, usually in your hands and feet. It can also affect other areas of your body. The cold sensation and numbness you're experiencing in your right upper thigh could be symptoms of peripheral neuropathy.

    • Treatment typically involves managing the condition causing your neuropathy. In some situations, over-the-counter pain relievers can help. For more severe symptoms, your doctor might recommend prescription medications.
  • Meralgia Paresthetica: This condition is caused by compression of the lateral femoral cutaneous nerve, which supplies sensation to your upper thigh. Symptoms include tingling, numbness, and a burning sensation in the outer part of your thigh.

    • Treatment usually involves addressing the underlying cause of the nerve compression. For example, weight loss or wearing looser clothing can often help.
  • Circulatory Issues: Problems with blood circulation could cause cold sensations and numbness in certain parts of the body. Conditions like peripheral artery disease, which reduces blood flow to your limbs, could potentially be causing your symptoms.

    • Treatment usually involves lifestyle changes like exercising and eating a healthy diet. Medications or procedures to improve blood flow may also be necessary.

Please note that these are only possibilities and not a definitive diagnosis. It's important to consult with a healthcare provider for an accurate diagnosis.

What you can do

While waiting for your appointment with a healthcare provider, here are a few things you can do:

  1. Keep a symptom diary: Note down when you experience the cold sensation and numbness, how long it lasts, and any potential triggers. This can help your healthcare provider in diagnosing your condition.
  2. Stay active: Regular physical activity can improve circulation, which might help if your symptoms are due to a circulatory issue.
  3. Maintain a healthy weight: If your symptoms are due to meralgia paresthetica, maintaining a healthy weight can help relieve nerve compression.

What you should look out for

Please seek immediate medical attention if:

  • Your symptoms worsen or spread to other parts of your body
  • You experience severe pain
  • You have difficulty walking or moving your leg
  • You notice changes in the color or temperature of your leg

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for accurate information.

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11 mo ago

People Also Ask


What is peripheral neuropathy and what are its common symptoms?

Peripheral neuropathy is a condition resulting from damage to the peripheral nerves, often causing weakness, numbness, and pain, usually in the hands and feet. It can also affect other areas of the body, leading to symptoms like tingling, burning, or a cold sensation.


How is meralgia paresthetica diagnosed and treated?

Meralgia paresthetica is diagnosed through a physical examination and sometimes imaging tests to rule out other conditions. Treatment typically involves addressing the underlying cause of nerve compression, such as weight loss or wearing looser clothing. In some cases, medications or physical therapy may be recommended.


What lifestyle changes can help improve circulatory issues?

Lifestyle changes that can help improve circulatory issues include regular physical activity, maintaining a healthy diet, quitting smoking, and managing stress. These changes can enhance blood flow and reduce the risk of conditions like peripheral artery disease.


When should I seek immediate medical attention for numbness and cold sensations in my thigh?

You should seek immediate medical attention if your symptoms worsen or spread, if you experience severe pain, have difficulty walking or moving your leg, or notice changes in the color or temperature of your leg. These could be signs of a more serious condition requiring prompt evaluation.


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