[58F] Sudden onset of widespread itchy rash with bumps

Patient Description

A 58-year-old female with a medical history of Hypothyroidism since 2008 and Sjogren's syndrome diagnosed in 2017, who has undergone chemotherapy for lymphomas in the salivary gland area 5 months ago, reports a sudden onset of an itchy rash with red bumps of different sizes all over her body, including forearms, lower back, armpits, neck, chest, biceps, legs, and calves. The rash started approximately 10 minutes before the encounter. The patient has managed the itchiness with a paste of baking soda and water and has taken two allergy pills. The patient is currently on Levothyroxine, Cequa eye drops, and Salagen. There is no known contact with anyone with a similar condition, no recent travel, no use of new skin products, and no known allergies to medications. The patient does not report any difficulty breathing, swelling of the face or mouth, or feeling faint or lightheaded.

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Arora's Assessment

What might be happening

Based on the information you've provided, the sudden onset of a widespread, itchy rash and bumps could be due to a number of conditions:

  • Allergic Reaction: This could be a reaction to something you've eaten, inhaled, or come into contact with. Allergic reactions can cause hives, which are red, itchy bumps that appear suddenly.

    • Treatment typically involves avoiding the allergen and taking antihistamines to control symptoms.
  • Drug Reaction: Certain medications can cause a rash as a side effect. Given that you've recently taken allergy pills, it's possible that this could be a reaction to those pills.

    • Treatment involves discontinuing the medication (under the guidance of a healthcare professional) and managing symptoms.
  • Viral Exanthem: Many viral infections can cause a rash, although this is less likely given the sudden onset and absence of other symptoms like fever or fatigue.

  • Dermatitis: This is inflammation of the skin that can be caused by a variety of factors, including irritants or allergens.

    • Treatment typically involves avoiding the irritant/allergen and applying topical creams to manage symptoms.

Given your medical history of Sjogren's syndrome, it's also possible that this could be related. Some people with Sjogren's can develop a rash, although this is less common.

What you can do

You should seek immediate medical attention given the sudden onset of your symptoms. In the meantime, continue to avoid scratching the rash as this can worsen the inflammation and potentially lead to infection. Over-the-counter creams and ointments may help to alleviate the itchiness.

What you should look out for

Seek immediate medical attention if:

  • The rash continues to spread or worsen
  • You develop other symptoms such as difficulty breathing, swelling of the face or mouth, or a fever
  • The rash does not improve after a few days

Please remember that while I strive to provide accurate information, I am an AI and not a doctor. Always consult with a healthcare professional for a formal diagnosis and treatment.

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11 mo ago

People Also Ask


What are common causes of sudden itchy rashes with red bumps?

Common causes of sudden itchy rashes with red bumps include allergic reactions, drug reactions, viral infections, and dermatitis. Identifying the trigger is crucial for effective treatment.


Can medications cause sudden skin rashes?

Yes, certain medications can cause skin rashes as a side effect. It's important to consult a healthcare professional to determine if a medication is the cause and to discuss alternative treatments.


How can Sjogren's syndrome affect the skin?

Sjogren's syndrome can sometimes lead to skin issues, including rashes, due to its autoimmune nature. However, skin rashes are less common compared to other symptoms like dry eyes and mouth.


What immediate actions should be taken if a rash suddenly appears?

If a rash suddenly appears, it's important to avoid scratching, apply soothing creams or ointments, and take antihistamines if advised. Seek medical attention if the rash spreads, or if there are symptoms like difficulty breathing or swelling.


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