[49M] With balance issues, tremors, and muscle weakness

Patient Description

A 49-year-old male has been experiencing a progressive loss of balance over the past 8 months, particularly when walking, turning, or getting up from bed. Physical therapy has not been effective. He reports episodes of loss of balance while standing, especially with eyes closed, and during tandem walking. The patient also has difficulty walking, with legs giving out due to overuse of leg muscles. Muscle weakness is noted in the right arm and both legs. Tremors are present, more pronounced in the left hand but also occurring in the right hand, with both arms shaking involuntarily off and on. The tremors are constant and lack rhythm, and they worsen when performing tasks such as fastening a belt or reaching out in front. Additionally, the patient experiences blurred vision, which has worsened over time, watery eyes, increased urinary frequency, and difficulty with coordination and fine motor skills. There is no history of recent head injuries, ear infections, changes in hearing, or ringing in the ears. The patient has not been diagnosed with any neurological conditions, nor has he had any neurological evaluations. There is no known family history of neurological conditions, and he is not currently taking any medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, several potential diagnoses could explain your condition. Here are the most likely ones:

  1. Parkinson's Disease:

    • Rationale: Parkinson's disease often presents with tremors, muscle weakness, and balance issues. The tremors are typically more pronounced at rest and can affect both hands and arms. The progression of symptoms over 8 months and the involvement of fine motor skills (e.g., fastening a belt) are also consistent with this condition.
    • Typical Treatments/Testing: Diagnosis usually involves a neurological examination and may include imaging tests like MRI or DaTscan. Treatment often includes medications like levodopa or dopamine agonists, and physical therapy can help manage symptoms.
  2. Multiple Sclerosis (MS):

    • Rationale: MS can cause a wide range of neurological symptoms, including muscle weakness, balance issues, tremors, and blurred vision. The progressive nature of your symptoms and the involvement of multiple body systems (e.g., vision, muscle control) could be indicative of MS.
    • Typical Treatments/Testing: Diagnosis often involves MRI scans, lumbar puncture, and evoked potential tests. Treatment may include disease-modifying therapies, steroids for relapses, and symptomatic treatments like physical therapy.
  3. Essential Tremor:

    • Rationale: Essential tremor is a neurological disorder that causes involuntary and rhythmic shaking, particularly in the hands and arms. It can worsen with movement and affect daily activities like fastening a belt.
    • Typical Treatments/Testing: Diagnosis is usually clinical, based on the pattern of tremors. Treatment may include medications like propranolol or primidone, and in severe cases, surgical options like deep brain stimulation.

What you can do

Loss of Balance and Altered Gait

  • See a Neurologist: Given the severity and progression of your symptoms, it's crucial to consult a neurologist for a comprehensive evaluation. They may recommend imaging tests and other diagnostic procedures.
  • Safety Measures: Use assistive devices like a cane or walker to prevent falls. Ensure your home is free of tripping hazards.
  • Physical Therapy: Although it hasn't helped so far, a specialized program focusing on balance and coordination might still be beneficial.

Tremors and Muscle Weakness

  • Medication: Depending on the diagnosis, medications like beta-blockers, anticonvulsants, or dopamine agonists may be prescribed.
  • Occupational Therapy: This can help you adapt daily activities to manage tremors and muscle weakness more effectively.
  • Relaxation Techniques: Stress can exacerbate tremors, so techniques like deep breathing, meditation, or yoga may help.

Blurry Vision

  • Eye Examination: Consult an ophthalmologist to rule out any eye-specific issues and to get appropriate treatment.
  • Manage Dry Eyes: Use over-the-counter artificial tears to alleviate watery eyes and blurred vision.

Increased Urination

  • Urologist Consultation: Increased urination can be a symptom of various conditions, including neurological disorders. A urologist can help determine the cause and recommend treatment.
  • Fluid Management: Monitor your fluid intake and try to avoid diuretics like caffeine and alcohol.

General Tips

  • Symptom Journal: Use MDandMe to journal your symptoms, track progress, and get insights. This can be very helpful for your healthcare provider to understand the progression and impact of your symptoms.
  • Healthy Lifestyle: Maintain a balanced diet, stay hydrated, and engage in regular, gentle exercise as tolerated.

What you should look out for

Given the complexity and severity of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Sudden Worsening of Symptoms: Any rapid deterioration in your balance, vision, or muscle strength.
  • New Symptoms: Development of new symptoms like severe headaches, changes in consciousness, or severe pain.
  • Falls or Injuries: Any falls or injuries resulting from your balance issues should be evaluated immediately.

Remember, while I can provide information and suggestions, it's essential to consult with a healthcare professional for a formal diagnosis and treatment plan.

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People Also Ask


What are the common symptoms of Parkinson's Disease?

Common symptoms of Parkinson's Disease include tremors, muscle stiffness, slowness of movement, balance problems, and changes in speech and writing. Symptoms often start gradually and worsen over time.


How is Multiple Sclerosis diagnosed?

Multiple Sclerosis is diagnosed through a combination of clinical evaluation, MRI scans to detect lesions in the brain and spinal cord, lumbar puncture to analyze cerebrospinal fluid, and evoked potential tests to measure electrical activity in the brain.


What treatments are available for Essential Tremor?

Treatments for Essential Tremor may include medications such as propranolol or primidone to reduce tremors. In severe cases, surgical options like deep brain stimulation may be considered. Lifestyle changes and physical therapy can also help manage symptoms.


What could cause increased urinary frequency in neurological conditions?

Increased urinary frequency in neurological conditions can be caused by disruptions in the nervous system's control over the bladder. Conditions like Multiple Sclerosis or Parkinson's Disease can affect the nerves that regulate bladder function, leading to symptoms such as urgency, frequency, or incontinence.


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