[49F] With severe muscle aches, joint swelling, and systemic symptoms

Patient Description

A 49-year-old female presents with severe muscle aches from head to toe, a stiff neck, and swelling of the lymph nodes on both sides of her neck. The lymph nodes are firm but not large, and the swelling began today. She reports muscular pain in her neck, back, and both legs for the past two days, described as deep throbbing pain rated 6-7 out of 10. Additionally, she has experienced joint pain and swelling in her elbows, knees, and shoulders for about a month, with the pain being mostly dull but occasionally sharp. Neither Advil nor Tylenol has provided much relief. The patient has had fever, fatigue, fluctuating appetite, and difficulty sleeping. She reports changes in bowel and bladder habits, such as drinking a lot of water but not urinating much. She has also experienced headaches, dizziness, and changes in vision, with headaches being constant for a couple of days last week and now more intermittent. She has neuropathy in her legs, arms, hands, and face, causing numbness and tingling. Additionally, she pulled a muscle in her chest while picking up her puppy and has asthma. Her medical history includes fibromyalgia, and she is currently taking Desvenlaflaxine (30 mg once daily) and Gabapentin (previously 270 mg three times daily, but she has reduced the dosage herself). She has no known allergies to medications. She has not received her flu shot or COVID-19 vaccine this year and lives alone but has had contact with someone who was not feeling well.

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Arora's Assessment

What might be happening

Based on the symptoms and history you've provided, here are some possible explanations for what might be happening:

Severe Muscle Aches, Stiff Neck, and Swollen Lymph Nodes

  • Infection: Given your history of battling infections due to broken teeth, it's possible that a systemic infection is causing your muscle aches, stiff neck, and swollen lymph nodes. Infections can lead to widespread inflammation and immune response.
  • Fibromyalgia Flare-Up: While you mentioned that this feels different from your usual fibromyalgia symptoms, it's possible that stress or infection is exacerbating your condition.
  • Autoimmune Disease: Conditions like rheumatoid arthritis (which your sister has) or lupus can cause muscle pain, joint swelling, and systemic symptoms like fever and fatigue.

Joint Pain and Swelling

  • Rheumatoid Arthritis: This autoimmune condition can cause joint pain, swelling, and systemic symptoms like fatigue and fever. Given your family history, this is a possibility.
  • Infection-Related Arthritis: Infections can sometimes lead to reactive arthritis, causing joint pain and swelling.

Weight Loss, Fatigue, and Immune System Concerns

  • Chronic Infection: Ongoing infections can lead to weight loss, fatigue, and a weakened immune system.
  • Autoimmune Disease: Conditions like lupus or rheumatoid arthritis can cause systemic symptoms, including weight loss and fatigue.

Headaches, Dizziness, and Vision Changes

  • Systemic Infection or Inflammation: These symptoms can be related to a systemic infection or an inflammatory condition affecting multiple body systems.
  • Medication Side Effects: Some of your symptoms could be related to side effects from medications like Gabapentin.

What you can do

Severe Muscle Aches, Stiff Neck, and Swollen Lymph Nodes

  • See a Doctor: Given the severity and sudden onset of your symptoms, it's important to see a healthcare provider as soon as possible. They may perform blood tests, imaging, or other diagnostic tests to determine the cause.
  • Rest and Hydrate: Ensure you get plenty of rest and stay hydrated to support your immune system.
  • Over-the-Counter Pain Relief: Continue using over-the-counter pain relievers like Advil or Tylenol, but follow the recommended dosage.

Joint Pain and Swelling

  • Consult a Rheumatologist: Given the possibility of an autoimmune condition, seeing a specialist like a rheumatologist could be beneficial.
  • Apply Ice or Heat: Use ice packs or heating pads on swollen joints to reduce pain and inflammation.
  • Gentle Exercise: Engage in gentle exercises like stretching or yoga to maintain joint mobility.

Weight Loss, Fatigue, and Immune System Concerns

  • Nutrient-Rich Diet: Eat a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support your immune system.
  • Monitor Symptoms: Keep track of your symptoms, weight, and any changes using the MDandMe journal. This can help your healthcare provider understand your condition better.

Headaches, Dizziness, and Vision Changes

  • Stay Hydrated: Ensure you drink enough water throughout the day.
  • Limit Screen Time: Reduce screen time to alleviate eye strain and headaches.
  • Consult an Eye Specialist: Given your history of eye surgery and current vision changes, seeing an eye specialist may be helpful.

What you should look out for

Given the complexity and severity of your symptoms, it's important to seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • High Fever: If your fever becomes very high or persistent.
  • Severe Pain: If your pain becomes unbearable or significantly worsens.
  • Difficulty Breathing: If you experience shortness of breath or chest pain.
  • Neurological Symptoms: If you experience new or worsening numbness, tingling, or weakness.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment. If you have more questions or need further assistance, feel free to continue the conversation.

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7 mo ago

People Also Ask


What could be causing my severe muscle aches and swollen lymph nodes?

Severe muscle aches and swollen lymph nodes could be due to a systemic infection, a flare-up of fibromyalgia, or an autoimmune disease like rheumatoid arthritis or lupus. It's important to consult a healthcare provider for a proper diagnosis.


Why am I experiencing joint pain and swelling, and could it be related to an autoimmune condition?

Joint pain and swelling could be caused by rheumatoid arthritis, especially given your family history, or it could be reactive arthritis related to an infection. Seeing a rheumatologist for further evaluation would be beneficial.


What should I do about my persistent headaches, dizziness, and vision changes?

Persistent headaches, dizziness, and vision changes could be related to a systemic infection, inflammation, or medication side effects. It's advisable to stay hydrated, limit screen time, and consult an eye specialist, especially given your history of eye surgery.


How can I manage my symptoms of fatigue and weight loss effectively?

To manage fatigue and weight loss, ensure a nutrient-rich diet, stay hydrated, and monitor your symptoms closely. Consulting with a healthcare provider can help address any underlying conditions contributing to these symptoms.


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