[46M] With chronic abdominal and testicular pain

Patient Description

A 46-year-old male has been experiencing severe, constant pain in the right abdomen and right testicle area for about seven years, worsening over the last two years. The pain is described as sharp, stabbing, burning, throbbing, and constant, exacerbated by thoughts or attempts of sexual activity, stress, or yelling. The patient had the right testicle removed, but the pain persists, with slight swelling in the remaining testicle. Despite ultrasounds and antibiotics, there is no relief. Nerve medication was ineffective, and the patient resorts to high doses of ibuprofen. There is difficulty urinating, requiring manual assistance. No fever, chills, blood in urine, weight loss, or appetite loss reported. Diagnosed with high blood pressure and high liver enzymes since age 18, the patient takes amlodipine, benazepril, and atorvastatin daily, along with ibuprofen and a baby aspirin. Experiences dizziness when standing but has no known drug allergies.

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Arora's Assessment

What might be happening

Your symptoms suggest a complex issue that may involve multiple factors:

  1. Chronic Pain Syndrome: Given the duration and severity of your pain, it might be part of a chronic pain syndrome. This can occur even after surgery, like testicle removal, due to nerve damage or other factors.

  2. Nerve Pain (Neuropathy): The sharp, burning, and throbbing nature of your pain could indicate nerve involvement. This might explain why typical pain medications haven't been effective.

  3. Pelvic Floor Dysfunction: Difficulty urinating and pain during sexual activity might be related to pelvic floor issues, which can cause referred pain to the abdomen and testicle area.

  4. Medication Side Effects: High doses of ibuprofen and other medications can contribute to gastrointestinal issues and may not effectively manage nerve-related pain.

What you can do

Pain Management:

  • Consult a Pain Specialist: Seek a pain management specialist who can explore alternative treatments like nerve blocks, physical therapy, or non-opioid medications.
  • Consider Non-Medication Therapies: Techniques like cognitive behavioral therapy, acupuncture, or biofeedback might offer some relief.

Lifestyle Adjustments:

  • Diet and Hydration: Ensure a balanced diet and adequate hydration to help manage constipation and overall health.
  • Gentle Exercise: Engage in gentle exercises, like walking or stretching, to improve circulation and reduce stress.

Medication Review:

  • Discuss with Your Doctor: Review your current medications with your healthcare provider to address side effects like dizziness and explore alternatives.

Symptom Tracking:

  • Use MDandMe: Journal your symptoms, track progress, and share insights with your healthcare provider to help guide treatment decisions.

What you should look out for

  • Seek Immediate Care: If you experience new symptoms like fever, severe swelling, or changes in urination, seek medical attention promptly.
  • Monitor for Side Effects: Be aware of any new side effects from medications and report them to your doctor.

Remember, it's important to work closely with healthcare professionals to find a treatment plan that works for you.

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3 mo ago

People Also Ask


What could be causing chronic pain even after testicle removal?

Chronic pain after testicle removal could be due to nerve damage or chronic pain syndrome, where the nervous system continues to send pain signals even after the initial cause has been treated.


Why might nerve pain medications be ineffective for some patients?

Nerve pain medications may be ineffective if the pain is not solely due to nerve issues or if the specific medication does not target the underlying cause of the pain. It may require a combination of treatments or alternative therapies.


How can pelvic floor dysfunction affect urination and sexual activity?

Pelvic floor dysfunction can lead to muscle tension or spasms, which may cause difficulty urinating and pain during sexual activity. This can result in referred pain to the abdomen and testicle area.


What are the potential side effects of long-term ibuprofen use?

Long-term use of ibuprofen can lead to gastrointestinal issues such as ulcers or bleeding, kidney damage, and increased risk of heart problems. It's important to use it under medical supervision and explore other pain management options.


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