[45F] Experiencing a range of chronic symptoms

Patient Description

A 45-year-old female presents with a history of neck and jaw muscle tightness rated 7/10 for severity, persisting for 20 years and exacerbated by stress, exercise, and cold. She experiences night sweats 1-2 times weekly, significant unintentional weight loss of 62 lbs in 10 months, and cognitive difficulties post-COVID-19 since 2020. The patient reports chronic joint pain in the shoulder, neck, and back, with the shoulder pain described as sharp and currently rated 7.5/10. Hair thinning has been noted since 2020, with increased severity in the past year. She has a continuous migraine syndrome with an 11-year history, rating headache severity as 8.5/10. Tinnitus started 6 months ago, described as a low buzzing sound rated 3/10. Sleep is disrupted despite medication, with frequent awakenings and persistent fatigue. The patient also reports easy bruising, narcolepsy, low prolactin, difficulty swallowing associated with an enlarged thyroid, cold intolerance, overheating, anxiety, and some depression. Known drug allergy to penicillin. Current medications include klonopin, tizanidine, naproxen, singular, montelukast, rosuvastatin, rizatriptan, ubrogepant, botox for migraine, and supplements such as vitamins D, B12, potassium, magnesium, and a probiotic.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Fibromyalgia: A disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues. It amplifies painful sensations by affecting the way your brain processes pain signals. The symptoms you've described, such as muscle tightness, joint pain, fatigue, and cognitive difficulties (often referred to as "fibro fog"), are common in fibromyalgia.

    • Treatment often involves a combination of medications, exercise, stress-reduction measures, and cognitive behavioral therapy.
  • Hypothyroidism: A condition where your thyroid doesn't produce enough thyroid hormones. It can cause a variety of symptoms, such as fatigue, joint or muscle pain, cold intolerance, and hair thinning. Given your report of an enlarged thyroid, this could be a possibility.

    • Treatment typically involves daily use of the synthetic thyroid hormone levothyroxine.
  • Menopause: The end of a woman's menstrual cycles, typically occurring between ages 45 and 55. Symptoms can include irregular periods, night sweats, sleep difficulties, mood changes, and thinning hair.

    • Treatment can involve hormone therapy, medications, lifestyle changes, and alternative therapies.
  • Chronic Fatigue Syndrome (CFS): A complicated disorder characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue worsens with physical or mental activity, but doesn't improve with rest. Symptoms can include those you've described, such as fatigue, sleep problems, and joint pain.

    • Treatment focuses on symptom relief.
  • Anxiety and Depression: Mental health disorders that can cause a range of symptoms, including difficulty sleeping, fatigue, and difficulty concentrating. You've mentioned experiencing anxiety and some depression.

    • Treatment can involve psychotherapy, medications, and lifestyle changes.

Please remember that these are only possibilities and not a definitive diagnosis. It's important to discuss these symptoms with a healthcare provider who can evaluate you fully and guide you through the process of reaching a diagnosis.

What you can do

  1. Schedule an appointment with your healthcare provider to discuss your symptoms. They may refer you to a specialist, such as a rheumatologist, endocrinologist, or psychiatrist, depending on your symptoms.
  2. Keep a symptom diary. This can help you and your healthcare provider identify patterns and triggers for your symptoms.
  3. Practice good sleep hygiene. This includes maintaining a regular sleep schedule, creating a quiet and comfortable sleep environment, and avoiding caffeine and electronics before bed.
  4. Stay active. Regular physical activity can help manage symptoms such as fatigue, pain, and mood changes.
  5. Eat a balanced diet. Good nutrition can support your body's overall health and resilience.

What you should look out for

Please seek immediate medical attention if you experience:

  • Severe pain or swelling in your joints
  • Difficulty breathing or chest pain
  • Severe headache or a headache that is different from your usual migraines
  • Thoughts of harming yourself or others

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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11 mo ago

People Also Ask


What are the common symptoms of fibromyalgia?

Common symptoms of fibromyalgia include widespread musculoskeletal pain, fatigue, sleep disturbances, cognitive difficulties (often called 'fibro fog'), and mood issues. It can also cause headaches, irritable bowel syndrome, and sensitivity to noise, light, or temperature.


How can hypothyroidism affect my overall health?

Hypothyroidism can lead to a variety of symptoms such as fatigue, weight gain, cold intolerance, joint and muscle pain, dry skin, hair thinning, depression, and an enlarged thyroid (goiter). It can also affect heart rate and cholesterol levels.


What are the typical signs of menopause?

Typical signs of menopause include irregular periods, hot flashes, night sweats, sleep disturbances, mood changes, thinning hair, and vaginal dryness. Some women may also experience weight gain and changes in libido.


How is chronic fatigue syndrome diagnosed and managed?

Chronic fatigue syndrome is diagnosed based on a thorough medical history and physical examination, as there is no specific test for it. Management focuses on symptom relief and may include medications, cognitive behavioral therapy, graded exercise therapy, and lifestyle changes to improve sleep and reduce stress.


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