[44F] With swollen lymph nodes, fatigue, ear pain, and intermittent rash

Patient Description

A 44-year-old female presents with swollen lymph nodes in the groin and neck, fatigue, and ear pain that started a few days ago. The patient also reports a dry splotchy rash on the right forearm that is scaly with round patches of darker color, which began around November and is intermittently bothersome. The rash does not respond well to hydrocortisone cream but is somewhat alleviated by scratching. The patient has experienced significant weight loss over the past 5-6 months, going from a size 12 to a size 6. The patient is an ex-smoker with no significant medical history since childhood. Known drug allergies include Augmentin, Keflex, Levaquin, and plastic tape. The patient is not currently on any medications.

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Arora's Assessment

What might be happening

Based on the information you have provided, possible diagnoses include:

  • Lymphoma: This is a type of cancer that begins in the lymphatic system. The lymphatic system is part of the body's germ-fighting network. The most common symptom is a painless swelling in a lymph node. Other symptoms can include fatigue, weight loss, and skin rash.

    • Diagnosis typically involves a physical exam, blood tests, imaging tests, and a lymph node biopsy. Treatment usually involves chemotherapy, radiation therapy, and in some cases, stem cell transplant.
  • HIV/AIDS: This is a viral infection that damages your immune system and can lead to AIDS. Symptoms can include swollen lymph nodes, fatigue, weight loss, and skin rash.

    • Diagnosis involves blood tests and sometimes saliva tests. Treatment involves antiretroviral therapy to manage the virus.
  • Lupus: This is a systemic autoimmune disease that occurs when your body's immune system attacks your own tissues and organs. Symptoms can include fatigue, weight loss, skin rash, and swollen lymph nodes.

    • Diagnosis typically involves a physical exam, blood tests, and sometimes a skin or kidney biopsy. Treatment usually involves NSAIDs, corticosteroids, antimalarial drugs, and immunosuppressants.
  • Mononucleosis: This is a viral infection that causes symptoms such as fatigue, swollen lymph nodes, and sometimes a skin rash.

    • Diagnosis involves a physical exam and blood tests. Treatment usually involves rest, hydration, and over-the-counter remedies for symptoms.

Please note that these are possibilities based on the information you've provided and not a definitive diagnosis.

What you can do

  1. Make an appointment with your primary care doctor as soon as possible. They can perform a physical exam and order tests to help determine what might be causing your symptoms.
  2. Keep track of your symptoms. Write down when they occur, how long they last, and any other details that might help your doctor.
  3. Stay hydrated and eat a balanced diet. This can help manage your fatigue and support your overall health.

What you should look out for

Seek immediate medical attention if you experience:

  • Severe abdominal pain
  • Difficulty breathing
  • High fever (over 101.5°F)
  • Sudden, severe headache
  • Any new or worsening symptoms

Remember, I'm an AI and this advice is based on the information you've given me. It's always important to consult with a healthcare professional for an accurate diagnosis.

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11 mo ago

People Also Ask


What are the common symptoms of lymphoma?

Common symptoms of lymphoma include painless swelling of lymph nodes, fatigue, unexplained weight loss, fever, night sweats, and sometimes skin rashes. Diagnosis typically involves a physical exam, blood tests, imaging tests, and a lymph node biopsy.


How is HIV/AIDS diagnosed and treated?

HIV/AIDS is diagnosed through blood tests that detect the presence of the virus or antibodies against it. Treatment involves antiretroviral therapy (ART), which helps manage the virus and maintain immune function.


What are the typical signs of lupus?

Typical signs of lupus include fatigue, joint pain, skin rashes (often a butterfly-shaped rash on the face), fever, and swollen lymph nodes. Diagnosis involves a combination of physical exams, blood tests, and sometimes biopsies.


What should I do if I suspect I have mononucleosis?

If you suspect you have mononucleosis, you should see a doctor for a physical exam and blood tests. Treatment mainly involves rest, staying hydrated, and using over-the-counter medications to relieve symptoms like fever and sore throat.


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