[44F] With persistent blood and mucus in stool, frequent bowel movements, and upper abdominal pain

Patient Description

A 44-year-old female has been experiencing blood and mucus in her stool for over a month. The blood is both dark and bright red, occurring multiple times a day, and sometimes there is no stool, just blood and mucus. She reports frequent bowel movements, especially after eating, occasional nausea, and pain in her upper abdomen, which she rates as 6 out of 10 in severity. The pain has occurred once or twice during the past month, and no relief has been found. She also experiences diarrhea, fever, and fatigue but has not noticed significant changes in weight or appetite, although she eats less to avoid frequent bathroom trips. She mentioned a skin rash, possibly a bite, and some joint pain due to pre-existing conditions. Her medical history includes ulcerative colitis, GERD, peptic ulcers, Degenerative Disc Disease, spine scoliosis, sciatica, ADHD, borderline personality disorder, depression, anxiety, PTSD, and gastrointestinal disease. She is allergic to tramadol and trazodone and is currently not taking any medications due to the passing of her previous doctor and not having found a new one yet.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Ulcerative Colitis Flare-Up: Given your history of ulcerative colitis, it's possible that you are experiencing a flare-up. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the digestive tract. Symptoms can include frequent diarrhea, blood and mucus in the stool, abdominal pain, and fatigue.

    • Treatment: Treatment typically involves medications to reduce inflammation and manage symptoms. These can include aminosalicylates, corticosteroids, immunomodulators, and biologics. In severe cases, surgery may be necessary.
  • Gastrointestinal Infection: Although you mentioned no recent travel or unusual food consumption, infections can still occur. Bacterial, viral, or parasitic infections can cause symptoms like diarrhea, blood in the stool, and abdominal pain.

    • Treatment: Treatment depends on the type of infection but may include antibiotics, antivirals, or antiparasitic medications. Hydration and rest are also important.
  • Peptic Ulcers: Given your history of peptic ulcers, it's possible that you have developed new ulcers or that existing ones have worsened. Peptic ulcers can cause bleeding, which may appear as blood in the stool.

    • Treatment: Treatment typically involves medications to reduce stomach acid, such as proton pump inhibitors (PPIs) or H2 blockers, and antibiotics if a bacterial infection (H. pylori) is present.
  • Colorectal Cancer: While less likely given your age, persistent blood in the stool can be a sign of colorectal cancer. This is especially a concern if you have a family history of gastrointestinal cancers.

    • Treatment: Treatment depends on the stage of cancer and may include surgery, chemotherapy, radiation therapy, or targeted therapy.

What you can do

  1. Consult a Doctor: It's crucial to consult a healthcare professional as soon as possible for a formal assessment and appropriate testing. This could include blood tests, stool tests, colonoscopy, or imaging studies.
  2. Dietary Adjustments: While waiting for your appointment, consider eating a bland diet to minimize irritation. Avoid spicy foods, caffeine, and alcohol.
  3. Stay Hydrated: Ensure you are drinking plenty of fluids to stay hydrated, especially if you are experiencing frequent diarrhea.
  4. Symptom Journal: Use MDandMe to journal your symptoms, track your progress, and share longitudinal medical notes with your healthcare provider. This can help in diagnosing and managing your condition.
  5. Rest: Make sure to get plenty of rest to help your body recover.

What you should look out for

Seek immediate medical attention if you experience any of the following:

  • Severe abdominal pain
  • High fever (temperature over 100.4°F)
  • Rapid weight loss
  • Dizziness or fainting
  • Increased frequency or severity of symptoms

Remember, while I can provide information and suggestions, I am not a substitute for a healthcare professional. Please consult a doctor for a formal diagnosis and treatment plan.

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5 mo ago

People Also Ask


What are the common symptoms of an ulcerative colitis flare-up?

Common symptoms of an ulcerative colitis flare-up include frequent diarrhea, blood and mucus in the stool, abdominal pain, fatigue, and sometimes fever. These symptoms can vary in severity and may require medical intervention to manage.


How can gastrointestinal infections be diagnosed and treated?

Gastrointestinal infections can be diagnosed through stool tests, blood tests, and sometimes imaging studies. Treatment depends on the type of infection and may include antibiotics for bacterial infections, antivirals for viral infections, or antiparasitic medications. Staying hydrated and resting are also important.


What are the potential complications of untreated peptic ulcers?

Untreated peptic ulcers can lead to serious complications such as bleeding, perforation of the stomach or intestinal wall, and gastric obstruction. These complications can cause severe pain, vomiting, and may require emergency medical treatment.


When should I be concerned about blood in my stool?

Blood in the stool can be concerning and should be evaluated by a healthcare professional, especially if it is persistent, accompanied by other symptoms like severe abdominal pain, weight loss, or if there is a family history of gastrointestinal cancers. Immediate medical attention is advised if symptoms worsen or new severe symptoms develop.


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