[43F] Experiencing unrelieved fatigue, hair loss, and weight gain

Patient Description

A 43-year-old female reports constant fatigue that has been progressively worsening over the past three months, not relieved by rest, and causing increased tiredness during daily activities. She has also noticed hair thinning, particularly at the back of her scalp, and weight gain during the same timeframe. Additionally, she experiences mood swings, with increased moodiness towards the end of the day. Other symptoms include cold intolerance, constipation, dry skin, and joint pain. Her medical history includes GERD diagnosed in 2010, and she is currently on Lexapro and Abilify. She has a known allergy to latex. No recent surgeries or changes in medication have been reported.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Hypothyroidism: This is a condition where the thyroid gland doesn't produce enough thyroid hormones. Symptoms can include fatigue, weight gain, hair loss, cold intolerance, constipation, dry skin, and joint pain. Mood changes, such as feeling more tearful or angry, can also occur.

    • Diagnosis typically involves a blood test to measure levels of thyroid-stimulating hormone (TSH) and possibly thyroid hormones themselves.
    • Treatment usually involves taking a daily hormone replacement tablet called levothyroxine.
  • Depression: This is a mood disorder that can cause persistent feelings of sadness and loss of interest in activities. It can also cause physical symptoms such as fatigue, weight changes, and sleep disturbances.

    • Diagnosis is usually based on a detailed discussion with a healthcare provider about your symptoms and feelings.
    • Treatment can involve a combination of medication, psychotherapy, and lifestyle changes.
  • Chronic Fatigue Syndrome (CFS): This is a complex disorder characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue is severe enough to interfere with daily activities and doesn't improve with rest.

    • Diagnosis is usually a process of ruling out other potential causes and the fatigue must be present for at least six months.
    • Treatment typically focuses on symptom relief.

Please note that these are potential diagnoses based on the information you've provided and should not be used as a definitive diagnosis. It's important to consult with a healthcare provider for a formal assessment.

What you can do

  1. Schedule an appointment with your primary care provider to discuss your symptoms. They may order tests, such as a blood test, to help determine the cause of your symptoms.
  2. Try to maintain a balanced diet and regular exercise routine, as these can help manage symptoms of fatigue and mood changes.
  3. Practice good sleep hygiene. This includes going to bed and waking up at the same time each day, avoiding caffeine and alcohol close to bedtime, and creating a quiet and comfortable sleep environment.
  4. Consider seeking support from a mental health professional, such as a psychologist or psychiatrist, who can provide strategies to manage mood changes.

What you should look out for

Seek immediate medical attention if you experience:

  • Thoughts of harming yourself or others
  • Severe worsening of your symptoms
  • New symptoms such as chest pain, shortness of breath, or severe abdominal pain

Remember, it's important to consult with a healthcare provider for a formal diagnosis and treatment plan.

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11 mo ago

People Also Ask


What are the common symptoms of hypothyroidism?

Common symptoms of hypothyroidism include fatigue, weight gain, hair loss, cold intolerance, constipation, dry skin, joint pain, and mood changes such as increased tearfulness or irritability.


How is hypothyroidism diagnosed?

Hypothyroidism is typically diagnosed with a blood test that measures levels of thyroid-stimulating hormone (TSH) and possibly thyroid hormones themselves.


What lifestyle changes can help manage symptoms of chronic fatigue syndrome?

Lifestyle changes that can help manage symptoms of chronic fatigue syndrome include maintaining a balanced diet, engaging in regular gentle exercise, practicing good sleep hygiene, and managing stress through relaxation techniques.


What should I do if I experience severe mood swings or thoughts of self-harm?

If you experience severe mood swings or thoughts of self-harm, it is important to seek immediate medical attention. Contact a healthcare provider or mental health professional for support and guidance.


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