[43F] Experiencing severe fatigue with respiratory and systemic symptoms

Patient Description

A 43-year-old female reports extreme fatigue, to the extent of sleeping approximately 90% of the day and being unable to get out of bed. This has been occurring since Saturday. Accompanying symptoms include nasal congestion, cough, headache, and a low-grade fever. The fatigue is severe, with no relief from any interventions thus far. There are no indications of recent weight changes. The patient's inability to stay awake for more than an hour at a time is the most troubling symptom, and there has been no improvement over the past few days.

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Arora's Assessment

What might be happening

Based on the information you've provided, you may be experiencing one of the following conditions:

  • Influenza (Flu): This is a common viral infection that can be deadly, especially in high-risk groups. The flu is different from a cold. Flu symptoms usually come on suddenly and may include fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, and fatigue.

    • Treatment typically involves rest and fluid to let the body fight the infection on its own. Over-the-counter anti-inflammatory pain relievers may help with symptoms. An annual vaccine can help prevent the flu and limit its complications.
  • COVID-19: This is a viral infection caused by a new coronavirus introduced to humans for the first time. It is spread from person to person mainly through the droplets produced when an infected person speaks, coughs or sneezes.

    • Treatment involves symptom relief and may include rest, fluid intake and pain relievers. You can protect yourself by washing your hands frequently, avoiding touching your face, and avoiding close contact (1 meter or 3 feet) with people who are unwell.
  • Mononucleosis: This is a viral infection that causes persistent fatigue, sore throat, fever and other symptoms. It's also called "mono" or "the kissing disease."

    • Treatment usually involves plenty of rest, good nutrition and drinking lots of fluids. You should feel better in a few weeks.

What you can do

You should seek immediate medical attention given your severe fatigue and inability to stay awake. In the meantime, try to stay hydrated and eat nutritious foods when you can.

What you should look out for

Seek immediate medical attention if you experience difficulty breathing, chest pain, confusion, or if your symptoms significantly worsen.

Please remember that this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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11 mo ago

People Also Ask


What are the common symptoms of influenza and how is it treated?

Common symptoms of influenza include sudden onset of fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, and fatigue. Treatment typically involves rest, fluids, and over-the-counter pain relievers. An annual flu vaccine can help prevent the flu.


How can I differentiate between COVID-19 and the flu based on symptoms?

Both COVID-19 and the flu can cause fever, cough, and fatigue, but COVID-19 may also include symptoms like loss of taste or smell, shortness of breath, and more severe respiratory issues. Testing is the most reliable way to differentiate between the two.


What is mononucleosis and how is it typically managed?

Mononucleosis, often called 'mono,' is a viral infection that causes persistent fatigue, sore throat, fever, and swollen lymph nodes. Management includes plenty of rest, good nutrition, and staying hydrated. Symptoms usually improve in a few weeks.


When should I seek medical attention for severe fatigue and other symptoms?

You should seek medical attention if you experience severe fatigue that prevents you from staying awake, difficulty breathing, chest pain, confusion, or if your symptoms significantly worsen. These could be signs of a more serious condition.


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