[40F] With tingling, swelling, and pain in hands, hair thinning, and weight loss

Patient Description

A 40-year-old female presents with tingling, swelling, and pain in her hands for the past four months. The tingling sensation, described as pins and needles, numbness, and burning, affects the whole hand but is more pronounced in the thumb and index finger. The pain, rated as 7 out of 10, is described as burning and sharp, like lightning, and sometimes extends from the hand to the elbow and armpit. The swelling in the hands has been present for about one to two weeks and can feel hot or sometimes cold. The patient reports difficulty with fine motor skills, such as buttoning a shirt or picking up small objects. Additionally, the patient has been experiencing hair thinning all over the scalp, weight loss, and one instance of distorted vision at night. The patient has a family history of autoimmune diseases, including rheumatoid arthritis, lupus, and thyroid disorders. Her past medical history includes Idiopathic Thrombocytopenic Purpura (ITP) and a splenectomy performed 20 years ago. She is not currently taking any medications and has no known allergies or adverse reactions to medications.

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Arora's Assessment

What might be happening

Based on the information you provided, several potential conditions could explain your symptoms:

  1. Carpal Tunnel Syndrome: This condition occurs when the median nerve, which runs from your forearm into the palm of your hand, becomes pressed or squeezed at the wrist. Symptoms include tingling, numbness, and pain in the thumb, index, and middle fingers, which can extend up the arm.

    • Treatment: Initial treatments often include wrist splinting, nonsteroidal anti-inflammatory drugs (NSAIDs), and corticosteroid injections. Severe cases may require surgery.
  2. Peripheral Neuropathy: This is a result of damage to the nerves outside of the brain and spinal cord and can cause pain, tingling, and weakness, often in the hands and feet. It can be caused by various factors, including diabetes, infections, and autoimmune diseases.

    • Treatment: Managing the underlying condition, pain relief medications, and physical therapy.
  3. Rheumatoid Arthritis: An autoimmune disorder that causes chronic inflammation of the joints, which can lead to pain, swelling, and deformity. It can also cause systemic symptoms like hair loss and weight loss.

    • Treatment: Disease-modifying antirheumatic drugs (DMARDs), biologics, and corticosteroids to reduce inflammation and slow disease progression.
  4. Lupus: Another autoimmune disease that can cause widespread inflammation and tissue damage in affected organs, including the skin, joints, and internal organs. Symptoms can include joint pain, hair loss, and weight loss.

    • Treatment: NSAIDs, corticosteroids, antimalarial drugs, and immunosuppressants.
  5. Thyroid Disorders: Both hyperthyroidism and hypothyroidism can cause symptoms like hair loss, weight changes, and tingling in the hands.

    • Treatment: Medications to normalize thyroid hormone levels, such as levothyroxine for hypothyroidism or antithyroid medications for hyperthyroidism.

What you can do

  1. Consult a Healthcare Provider: Given the range of symptoms and their potential seriousness, it is crucial to see a healthcare provider for a comprehensive evaluation. They may order blood tests, nerve conduction studies, or imaging tests to determine the underlying cause.
  2. Manage Symptoms: While awaiting a formal diagnosis, you can try the following:
    • Wrist Splints: Wearing wrist splints, especially at night, can help alleviate symptoms of carpal tunnel syndrome.
    • Anti-inflammatory Medications: Over-the-counter NSAIDs like ibuprofen can help reduce pain and swelling.
    • Hydration and Nutrition: Ensure you are well-hydrated and maintain a balanced diet to support overall health.
  3. Document Symptoms: Keep a symptom diary noting when your symptoms occur, their severity, and any potential triggers. This information can be valuable for your healthcare provider.

What you should look out for

Seek immediate medical attention if you experience any of the following:

  • Sudden, severe pain or loss of function in your hands or arms.
  • Signs of infection such as redness, warmth, and fever.
  • Rapidly worsening symptoms or new symptoms like difficulty breathing or chest pain.
  • Severe vision changes or loss of vision.

Remember, while this information can help guide you, it is not a substitute for professional medical advice. Please consult a healthcare provider for a formal diagnosis and appropriate treatment.

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5 mo ago


People Also Ask


What are the common symptoms of carpal tunnel syndrome?

Common symptoms of carpal tunnel syndrome include tingling, numbness, and pain in the thumb, index, and middle fingers, which can sometimes extend up the arm. These symptoms often worsen at night and can lead to difficulty with hand movements.


How can peripheral neuropathy be managed or treated?

Peripheral neuropathy can be managed by addressing the underlying cause, such as controlling blood sugar levels in diabetes. Pain relief can be achieved with medications like gabapentin or pregabalin, and physical therapy can help improve strength and coordination.


What are the potential causes of hair thinning and weight loss in autoimmune diseases?

In autoimmune diseases, hair thinning and weight loss can occur due to the body's immune system attacking its own tissues, leading to inflammation and metabolic changes. Conditions like lupus and rheumatoid arthritis are known to cause these symptoms.


What should I do if I experience sudden severe pain or loss of function in my hands?

If you experience sudden severe pain or loss of function in your hands, it is important to seek immediate medical attention. This could indicate a serious condition that requires prompt evaluation and treatment by a healthcare professional.

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