[40F] With chronic burning feet and recent leg pain

Patient Description

A 40-year-old female has been experiencing a constant burning sensation in her feet for over a year, which occurs all day and is not triggered by any specific activities. This sensation developed gradually over time. The patient has diabetes and has reported high blood sugar levels recently. Additionally, she has been experiencing sharp and throbbing leg pain for about a month, rated as 8 out of 10 in severity, without any recent injuries to the leg. The patient also reports tingling, muscle weakness, and difficulty walking or maintaining balance, but has not noticed any changes in the color or temperature of her feet or legs, nor any changes in bowel or bladder function. She has been feeling unusually fatigued. The patient is currently taking Lamictal (120 mg), Seroquel (200 mg), Clomipramine (100 mg), and Prazosin (2 mg) daily, and is not taking any over-the-counter medications, supplements, or herbal products.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

Burning Sensation in Feet

  1. Diabetic Neuropathy: Given your history of diabetes and high blood sugar levels, diabetic neuropathy is a likely cause. This condition occurs when high blood sugar damages nerves, leading to symptoms like burning, tingling, and numbness in the feet.
    • Typical Treatments: Managing blood sugar levels, medications like gabapentin or pregabalin, and lifestyle changes such as regular exercise and a balanced diet.

Leg Pain

  1. Peripheral Artery Disease (PAD): This condition occurs when the arteries in your legs become narrowed or blocked, leading to reduced blood flow and causing pain, especially during physical activity.
    • Typical Treatments: Lifestyle changes, medications to improve blood flow, and in some cases, surgical procedures.

Unifying Diagnosis

  1. Diabetic Neuropathy: This condition can explain both the burning sensation in your feet and the leg pain, as it affects the nerves in both areas.
  2. Peripheral Artery Disease (PAD): This condition can also cause both leg pain and burning sensations due to poor blood flow.

What you can do

Burning Sensation in Feet

  • Manage Blood Sugar: Keeping your blood sugar levels within the target range is crucial. Follow your diabetes management plan, including medication, diet, and exercise.
  • Foot Care: Inspect your feet daily for any cuts, blisters, or sores. Wear comfortable, well-fitting shoes and avoid walking barefoot.
  • Pain Management: Over-the-counter pain relievers like acetaminophen or ibuprofen may help. Consult your doctor for prescription medications if needed.

Leg Pain

  • Consult a Doctor: Given the severity of your pain, it's important to consult a healthcare provider. They may recommend tests like an ankle-brachial index (ABI) to check for PAD.
  • Exercise: Gentle, regular exercise like walking can improve blood flow and reduce symptoms. However, avoid overexertion.
  • Elevate Your Legs: Elevating your legs can help reduce pain and swelling.

General Tips

  • Healthy Diet: Follow a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. This can help manage both diabetes and overall health.
  • Stay Hydrated: Drink plenty of water to stay hydrated and support overall health.
  • Track Symptoms: Use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Given the severity of your symptoms and the potential for serious underlying conditions, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Worsening Pain: If your pain becomes more severe or unmanageable.
  • New Symptoms: If you experience new symptoms like chest pain, shortness of breath, or sudden weakness.
  • Infections: If you notice any signs of infection in your feet, such as redness, swelling, or discharge.

Remember, while I can provide information and suggestions, it's important to consult a healthcare professional for a formal diagnosis and treatment plan.

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3 mo ago


People Also Ask


What is diabetic neuropathy and how does it affect the feet?

Diabetic neuropathy is a type of nerve damage that can occur in people with diabetes. It often affects the feet and legs, causing symptoms like burning, tingling, numbness, and pain. Managing blood sugar levels and taking medications like gabapentin or pregabalin can help alleviate symptoms.


How can high blood sugar levels contribute to nerve damage?

High blood sugar levels can damage the small blood vessels that supply nerves, leading to nerve damage or neuropathy. This damage can cause symptoms such as burning, tingling, and numbness, particularly in the extremities like the feet.


What are the common symptoms and treatments for peripheral artery disease (PAD)?

Peripheral artery disease (PAD) is a condition where the arteries in the legs become narrowed or blocked, reducing blood flow. Common symptoms include leg pain, especially during physical activity, and burning sensations. Treatments include lifestyle changes, medications to improve blood flow, and sometimes surgical procedures.


How can lifestyle changes help manage symptoms of diabetic neuropathy and PAD?

Lifestyle changes such as maintaining a healthy diet, regular exercise, and proper foot care can help manage symptoms of diabetic neuropathy and PAD. These changes can improve blood sugar control, enhance circulation, and reduce the risk of complications.


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