[37F] Experiencing gastrointestinal and systemic symptoms

Patient Description

A 37-year-old female presents with a several-week history of nausea, particularly in the late afternoon or evening, rated as 7 out of 10 in severity and relieved by Zofran. She also reports intermittent sharp abdominal and flank pain, excessive sweating even at rest, a feeling of fullness after small meals, and fatigue. The patient has a history of lupus diagnosed in January 2017 and is currently on Plaquenil (200mg), Zoloft (100mg), Zofran, Vyvanse (75mg), and Losartan (100mg). There is a family history of gallbladder issues and cancer. The patient also noted a swollen lymph node last week. No fever, chills, vomiting, or significant weight loss reported. Stool is described as yellow and normal for the patient, with occasional variations. No allergies or adverse reactions to medications have been reported.

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Arora's Assessment

What might be happening

Based on the information you've provided, several conditions could be causing your symptoms:

  • Gastroparesis: This condition slows or stops the movement of food from your stomach to your small intestine. Symptoms can include nausea, vomiting, feeling full quickly when eating, abdominal bloating, and abdominal pain. Gastroparesis is often seen in people with diabetes, but it can also be associated with other conditions, including lupus.

    • Treatment typically involves dietary changes and medications to help your stomach empty more effectively.
  • Gallbladder disease: Given your family history of gallbladder problems and your symptoms of abdominal pain, nausea, and feeling full quickly, gallbladder disease could be a possibility. Gallstones or inflammation of the gallbladder can cause these symptoms.

    • Treatment may involve dietary changes, medications to dissolve gallstones, or surgery to remove the gallbladder.
  • Pancreatic conditions: Your pancreas is located in your upper abdomen and plays a key role in digestion. Conditions such as pancreatitis (inflammation of the pancreas) or pancreatic cancer can cause symptoms like abdominal pain, nausea, and changes in stool.

    • Treatment depends on the specific condition and may involve dietary changes, medications, or surgery.
  • Lupus flare: Lupus is a chronic autoimmune disease that can affect many parts of the body, including the digestive system. Your symptoms could be due to a lupus flare.

    • Treatment typically involves medications to reduce inflammation and manage symptoms.

Please note that these are possibilities based on the information you've provided, and they are not a definitive diagnosis.

What you can do

  1. Schedule an appointment with your healthcare provider to discuss your symptoms. They may want to perform tests, such as blood tests, imaging studies, or endoscopy, to help determine the cause of your symptoms.
  2. Keep a symptom diary. Note when your symptoms occur, what you're doing when they happen, and what foods you've eaten. This can help your healthcare provider identify patterns and potential triggers.
  3. Stay hydrated and eat small, frequent meals. This can help manage your symptoms of nausea and feeling full quickly.
  4. Continue taking your medications as prescribed, and let your healthcare provider know about all the medications you're taking.

What you should look out for

Seek immediate medical attention if you experience:

  • Severe abdominal pain
  • Persistent vomiting or inability to keep down fluids
  • Blood in your vomit or stool
  • Unexplained weight loss
  • Yellowing of your skin or eyes (jaundice)

Remember, I'm an AI and not a doctor. It's important to consult with a healthcare professional who can provide a definitive diagnosis and treatment plan based on a thorough evaluation of your symptoms and medical history.

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10 mo ago

People Also Ask


What is gastroparesis and how is it related to lupus?

Gastroparesis is a condition that affects the stomach muscles and prevents proper stomach emptying. It can be associated with lupus due to the autoimmune nature of the disease, which can affect the nerves controlling the stomach. Treatment often involves dietary changes and medications to improve gastric motility.


How can gallbladder disease be diagnosed and treated?

Gallbladder disease can be diagnosed through imaging tests like an ultrasound or CT scan, and blood tests to check for infection or inflammation. Treatment may include dietary changes, medications to dissolve gallstones, or surgery to remove the gallbladder if necessary.


What are the symptoms and treatment options for pancreatitis?

Pancreatitis is inflammation of the pancreas and can cause symptoms like severe abdominal pain, nausea, and vomiting. Treatment typically involves hospitalization, fasting to rest the pancreas, pain management, and sometimes surgery if there are complications.


What are the signs of a lupus flare and how can it be managed?

A lupus flare can present with increased fatigue, joint pain, skin rashes, and sometimes digestive issues. Management involves adjusting medications to control inflammation and symptoms, and working closely with a healthcare provider to monitor the condition.


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