[37F] Experiencing burning and itching in hands and feet triggered by cold

Patient Description

A 37-year-old female experiences severe burning and itching in her hands and feet when exposed to cold. The burning sensation is described as stinging and hot, occurring suddenly and lasting until she warms up. Her hands often go numb when holding objects for a minute or longer, with numbness lasting up to half an hour. She also experiences muscle tightness from shivering, which resolves upon warming. Color changes in her hands and feet include turning white and red during episodes. She has a family history of lupus and a personal medical history of asthma (diagnosed in 2020), PTSD (diagnosed in 2001), Substance Abuse Disorder (diagnosed in 2013), pelvic floor dysfunction, and FAI (both diagnosed in 2023). She is allergic to penicillin and is currently taking Methadone (33mg once daily), Albuterol (two puffs every 4-6 hours as needed), and Symbicort (two puffs every morning and night). No recent changes in medications or dosages, and no use of tobacco, alcohol, or recreational drugs.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some potential diagnoses and explanations:

  1. Raynaud's Phenomenon:

    • Explanation: Raynaud's phenomenon is a condition where small blood vessels in your extremities (like your hands and feet) overreact to cold or stress, causing them to narrow and limit blood supply. This can lead to color changes (white, blue, then red), burning, itching, and numbness.
    • Typical Treatments/Testing: Treatment often includes lifestyle changes to avoid cold exposure, medications to improve blood flow, and sometimes, addressing underlying conditions. A doctor might perform a physical exam and blood tests to rule out other conditions.
  2. Peripheral Neuropathy:

    • Explanation: Peripheral neuropathy involves damage to the peripheral nerves, which can cause burning, itching, and numbness. This can be due to various causes, including diabetes, infections, or autoimmune diseases.
    • Typical Treatments/Testing: Treatment focuses on managing the underlying cause and relieving symptoms. This might include medications, physical therapy, and lifestyle changes. A doctor might perform nerve conduction studies and blood tests.
  3. Autoimmune Conditions:

    • Explanation: Given your family history of lupus, it's possible that an autoimmune condition could be contributing to your symptoms. Autoimmune diseases can cause a wide range of symptoms, including those affecting the skin, nerves, and blood vessels.
    • Typical Treatments/Testing: Treatment depends on the specific autoimmune condition and may include medications to suppress the immune system and manage symptoms. Blood tests and imaging studies might be used for diagnosis.

What you can do

For Burning and Itching in Hands and Feet:

  • Avoid Cold Exposure: Try to keep your hands and feet warm. Wear gloves and warm socks, and avoid sudden temperature changes.
  • Gentle Warming: If you experience symptoms, gently warm your hands and feet using warm (not hot) water or a warm compress.
  • Moisturize: Use a good moisturizer to keep your skin hydrated and reduce itching.
  • Avoid Triggers: Identify and avoid other potential triggers, such as stress or certain activities.

For Numbness When Holding Objects:

  • Frequent Breaks: Take frequent breaks when holding objects to prevent prolonged pressure on your nerves.
  • Ergonomic Adjustments: Use ergonomic tools and grips to reduce strain on your hands.
  • Gentle Exercises: Perform gentle hand and wrist exercises to improve circulation and nerve function.

General Health:

  • Healthy Lifestyle: Maintain a healthy lifestyle with a balanced diet, regular exercise, and adequate sleep.
  • Symptom Tracking: Use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Given the severity and complexity of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Severe or Worsening Symptoms: If your symptoms become more severe or frequent.
  • New Symptoms: If you develop new symptoms, such as severe pain, significant color changes, or weakness.
  • Systemic Symptoms: If you experience systemic symptoms like fever, weight loss, or fatigue.

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and appropriate treatment. If you have any more questions or need further assistance, feel free to continue the conversation.

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4 mo ago


People Also Ask


What is Raynaud's Phenomenon and how is it treated?

Raynaud's Phenomenon is a condition where small blood vessels in the extremities overreact to cold or stress, causing them to narrow and limit blood supply. This can lead to color changes, burning, itching, and numbness. Treatment often includes avoiding cold exposure, using medications to improve blood flow, and addressing any underlying conditions.


What are the common causes and treatments for peripheral neuropathy?

Peripheral neuropathy involves damage to the peripheral nerves, which can cause burning, itching, and numbness. Common causes include diabetes, infections, and autoimmune diseases. Treatment focuses on managing the underlying cause and relieving symptoms, which might include medications, physical therapy, and lifestyle changes.


How can autoimmune conditions affect the hands and feet?

Autoimmune conditions can cause a wide range of symptoms, including those affecting the skin, nerves, and blood vessels in the hands and feet. These conditions can lead to symptoms like burning, itching, and numbness. Treatment depends on the specific autoimmune condition and may include medications to suppress the immune system and manage symptoms.


What lifestyle changes can help manage symptoms of cold-induced burning and itching in extremities?

To manage symptoms of cold-induced burning and itching in extremities, it is important to avoid cold exposure by wearing warm clothing, gently warm the affected areas using warm water or compresses, moisturize the skin to reduce itching, and identify and avoid other potential triggers such as stress.


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