[36M] With penile sores, oral thrush, and new facial blisters

Patient Description

A 36-year-old male presents with sores on his penis and thrush on his tongue for about a week, making it difficult to swallow. The penile sores are round, open, and blister-like, located on the foreskin, without any discharge or unusual smell. The patient reports recent unprotected sexual activity and gradual development of the sores. He also experiences pain in the pelvic area during bowel movements, swollen lymph nodes, constipation, and abdominal pain, but no fever, nausea, vomiting, or blood in the stool. The patient has no pre-existing conditions, chronic illnesses, or medications, and has not traveled recently to areas with known outbreaks of infectious diseases. Additionally, he noticed two small, dry, and itchy blisters forming on the side of his nostril in the crease, which started yesterday. He has not been around anyone with similar blisters and has not been tested for Herpes Simplex Virus (HSV) since his new partner.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

Sores on Penis and Blisters on Nostril

  • Herpes Simplex Virus (HSV): The round, open, blister-like sores on your penis and the dry, itchy blisters on your nostril are suggestive of HSV, a common sexually transmitted infection. HSV can cause painful sores and blisters in the genital area and around the mouth or nose. Testing for HSV typically involves a swab of the sores or a blood test.
  • Candidiasis (Thrush): The thrush on your tongue, which makes swallowing difficult, is likely due to a yeast infection caused by Candida. This can occur when the immune system is compromised or after antibiotic use. Treatment usually involves antifungal medications.

Swollen Lymph Nodes and Pelvic Pain

  • Infection: Swollen lymph nodes often indicate an infection. Given your symptoms, this could be related to HSV or another sexually transmitted infection.
  • Constipation and Abdominal Pain: These symptoms could be related to dietary factors, dehydration, or a gastrointestinal issue. However, they may also be exacerbated by the pain and discomfort from the sores and swollen lymph nodes.

What you can do

Sores on Penis and Blisters on Nostril

  • Seek Medical Attention: It's important to see a healthcare provider for a proper diagnosis and treatment. They may prescribe antiviral medications if HSV is confirmed.
  • Avoid Irritants: Keep the affected areas clean and dry. Avoid using harsh soaps or lotions that could irritate the sores.
  • Pain Relief: Over-the-counter pain relievers like ibuprofen can help manage pain and inflammation.

Thrush on Tongue

  • Antifungal Treatment: Your doctor may prescribe antifungal medications to treat the thrush. These can come in the form of lozenges, tablets, or mouthwash.
  • Maintain Oral Hygiene: Brush your teeth twice a day and use an antifungal mouthwash if recommended by your doctor.

Swollen Lymph Nodes and Pelvic Pain

  • Hydration and Diet: Drink plenty of water and eat a high-fiber diet to help with constipation. Foods rich in fiber include fruits, vegetables, and whole grains.
  • Warm Compress: Applying a warm compress to the swollen lymph nodes may help reduce discomfort.

General Tips

  • Avoid Sexual Activity: Until you have a clear diagnosis and treatment plan, it's best to avoid sexual activity to prevent spreading any potential infection.
  • Track Symptoms: Use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Given the severity and combination of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Fever or worsening symptoms
  • Increased pain or swelling
  • New or spreading sores or blisters
  • Difficulty breathing or swallowing

Remember, while I can provide guidance, it's crucial to consult a healthcare professional for a formal diagnosis and appropriate treatment.

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3 mo ago


People Also Ask


What are the common symptoms of Herpes Simplex Virus (HSV) infection?

Common symptoms of HSV infection include painful blisters or sores on the genitals, mouth, or nose, itching or tingling sensations before the sores appear, and sometimes flu-like symptoms such as fever and swollen lymph nodes.


How is oral thrush treated and what causes it?

Oral thrush is treated with antifungal medications, which can be in the form of lozenges, tablets, or mouthwash. It is caused by an overgrowth of Candida yeast, often due to a weakened immune system or after antibiotic use.


What could cause swollen lymph nodes and pelvic pain in this context?

Swollen lymph nodes and pelvic pain could be indicative of an infection, such as HSV or another sexually transmitted infection. Swollen lymph nodes are a common response to infection as the body fights off pathogens.


How can constipation and abdominal pain be managed effectively?

Constipation and abdominal pain can be managed by staying hydrated, eating a high-fiber diet, and using over-the-counter laxatives if necessary. It's also important to address any underlying causes, such as pain from sores or infections.

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