[35F] With soft, moveable lump and systemic symptoms

Patient Description

A 35-year-old female presents with a 10cm long, 1-inch wide, soft, and moveable lump near the bra line, noticed for a few weeks. The lump has not changed in size or shape. The patient also reports night sweats affecting the upper body for about a month, unintentional weight loss of approximately 8 pounds, itching, and hair loss. Additionally, she feels more tired than usual and has a small lump in the groin that comes and goes. The patient experiences swelling in the hands and feet in the heat but denies fever, chills, or persistent infections. She does not use tobacco, alcohol, or recreational drugs, and there have been no recent changes in her diet or eating habits. There is no recent travel history, and she is not currently on any medications. There is no family history of heart disease, stroke, autoimmune diseases, diabetes, cancer, or psychiatric illnesses, and she has no pre-existing conditions or chronic illnesses.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Lipoma: A lipoma is a benign (non-cancerous) tumor made of fat tissue. They are usually soft, movable, and painless. Lipomas are generally harmless and do not require treatment unless they cause discomfort or cosmetic concerns.

    • Treatment: If a lipoma is bothersome, it can be surgically removed. However, many people choose to leave them alone if they are not causing any issues.
  • Lymphoma: This is a type of cancer that begins in the lymphatic system. Symptoms can include painless swelling of lymph nodes, night sweats, unexplained weight loss, and fatigue. The presence of a lump near your bra line and a small lump in your groin, along with night sweats and weight loss, could be concerning for lymphoma.

    • Treatment: Treatment for lymphoma typically involves chemotherapy, radiation therapy, or a combination of both. A biopsy of the lump would be necessary to confirm the diagnosis.
  • Benign Cyst: Cysts are fluid-filled sacs that can develop in various parts of the body. They are usually benign and can be soft and movable.

    • Treatment: Cysts can be drained or surgically removed if they cause discomfort or other symptoms.
  • Dermatofibroma: This is a common benign skin growth that can feel firm and is usually painless. They can appear anywhere on the body and are often movable.

    • Treatment: Dermatofibromas generally do not require treatment unless they cause discomfort or cosmetic concerns. They can be surgically removed if necessary.

What you can do

While it's important to consult a healthcare professional for a formal diagnosis and treatment plan, here are some steps you can take in the meantime:

  1. Monitor the Lump: Keep an eye on the lump for any changes in size, shape, or texture. Take note of any new symptoms that may develop.
  2. Manage Night Sweats: Ensure your sleeping environment is cool and comfortable. Wear lightweight, breathable clothing to bed and use light bedding.
  3. Stay Hydrated: Drink plenty of water, especially if you are experiencing night sweats.
  4. Track Symptoms: Use MDandMe to journal your symptoms, track your progress, and get insights. This information can be very helpful for your healthcare provider.
  5. Healthy Diet: Maintain a balanced diet rich in fruits, vegetables, and lean proteins to support overall health.
  6. Rest: Ensure you are getting enough rest to help manage fatigue.

What you should look out for

It's important to seek medical attention if you notice any of the following:

  • Rapid Growth: If the lump grows rapidly or changes in appearance.
  • Pain or Tenderness: If the lump becomes painful or tender.
  • Additional Symptoms: If you develop new symptoms such as fever, chills, or unexplained weight loss.
  • Persistent Symptoms: If your night sweats, fatigue, or other symptoms persist or worsen.

Remember, while I can provide information and suggestions, it's crucial to consult a healthcare professional for a formal diagnosis and appropriate treatment. If you have any further questions or need more assistance, feel free to continue the conversation.

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5 mo ago


People Also Ask


What are the common causes of a soft, movable lump under the skin?

Common causes of a soft, movable lump under the skin include lipomas, benign cysts, and dermatofibromas. These are generally non-cancerous and often do not require treatment unless they cause discomfort.


What symptoms should prompt a visit to the doctor if I have a lump?

You should see a doctor if the lump grows rapidly, becomes painful or tender, or if you experience additional symptoms such as fever, chills, or unexplained weight loss.


How can night sweats be managed at home?

To manage night sweats at home, ensure your sleeping environment is cool and comfortable, wear lightweight, breathable clothing, and use light bedding. Staying hydrated is also important.


What are the potential causes of unintentional weight loss and fatigue?

Unintentional weight loss and fatigue can be caused by various factors, including stress, thyroid issues, infections, or more serious conditions like cancer. It's important to consult a healthcare professional for a proper diagnosis.


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