[34F] Experiencing severe calf pain, swelling, and coldness

Patient Description

A 34-year-old female presents with a 3-day history of gradually worsening pain in her left calf, described as shooting, pulsating, and twitching. The pain intensity varies, reaching a 10 when walking and subsiding to a 6 to 7 dull ache when sitting. The calf is slightly swollen, painful to touch, and colder compared to the other calf. There is no prior injury, and the patient denies any recent changes in skin color or temperature, shortness of breath, or chest pain. The patient has no known family history of blood clotting disorders, is not on oral contraceptives or hormone replacement therapy, and has no known allergies. Current medications include Wellbutrin, Adderall, and Xanax, taken for anxiety, with unspecified dosages. No other symptoms or pre-existing conditions were reported.

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Arora's Assessment

What might be happening

Based on the information provided, possible causes for your symptoms include:

  • Deep Vein Thrombosis (DVT): This condition occurs when a blood clot forms in one or more of the deep veins in your body, usually in your legs. DVT can cause leg pain and swelling, but it can also occur without noticeable symptoms. DVT is a serious condition because blood clots in your veins can break loose, travel through your bloodstream, and lodge in your lungs, blocking blood flow (pulmonary embolism).

    • Treatment typically involves anticoagulant medications to thin the blood and prevent further clotting. In severe cases, thrombolytic therapy (clot-dissolving medication) or surgical intervention may be needed.
  • Peripheral Artery Disease (PAD): This condition is characterized by reduced blood flow to your limbs due to narrowed arteries. PAD can cause pain and coldness in your leg, along with redness and swelling.

    • Treatment usually involves lifestyle changes, medications to control symptoms and prevent progression of the disease, and in severe cases, angioplasty or surgery.
  • Compartment Syndrome: This is a painful and potentially serious condition caused by pressure buildup from internal bleeding or swelling of tissues. It often occurs in an arm or leg and can lead to muscle and nerve damage if not treated promptly.

    • Treatment typically involves surgery to relieve the pressure.

What you can do

Given the severity of your symptoms and the potential seriousness of the conditions that could be causing them, it's important that you seek immediate medical attention.

While waiting for medical help:

  1. Try to keep your leg elevated.
  2. Avoid putting weight on the affected leg.
  3. Do not massage or apply heat to the affected area as this could potentially dislodge a blood clot if present.

What you should look out for

Seek immediate medical attention if:

  • Your symptoms worsen or do not improve.
  • You develop sudden or worsening shortness of breath, chest pain, or discomfort that worsens when you take a deep breath or when you cough.
  • You experience lightheadedness or fainting.

Please note that this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for accurate information.

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9 mo ago


People Also Ask


What are the common symptoms of Deep Vein Thrombosis (DVT)?

Common symptoms of DVT include swelling in one leg, pain or tenderness in the leg (often starting in the calf), a feeling of warmth in the affected leg, and changes in skin color such as redness. However, DVT can sometimes occur without noticeable symptoms.


How is Peripheral Artery Disease (PAD) diagnosed?

Peripheral Artery Disease is typically diagnosed through a combination of a physical exam, reviewing medical history, and tests such as the Ankle-Brachial Index (ABI), ultrasound, angiography, or blood tests to check for underlying conditions.


What are the risks of untreated Compartment Syndrome?

Untreated Compartment Syndrome can lead to permanent muscle and nerve damage due to prolonged pressure on the tissues. This can result in loss of function or even necessitate amputation in severe cases.


Can anxiety medications like Wellbutrin, Adderall, and Xanax affect leg pain or swelling?

While anxiety medications like Wellbutrin, Adderall, and Xanax are not directly known to cause leg pain or swelling, they can have side effects that might indirectly affect circulation or muscle tension. It's important to discuss any new or worsening symptoms with a healthcare provider.


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