[33F] With persistent breast pain and other symptoms

Patient Description

A 33-year-old female has been experiencing persistent breast pain throughout both breasts for the past four weeks, rated as 6 out of 10 in severity. The pain occurs continuously all day long without any specific activities or injuries exacerbating it. She also reports nausea, for which she has been prescribed medication, and fatigue, feeling tired all the time. Additionally, she has been experiencing random episodes of insomnia, periodic cramps in the lower stomach that lasted for about three and a half weeks but have now stopped, and a missed period, which is five days late. She has noticed changes in her appetite, where certain foods make her feel nauseous just by thinking about them, as well as mood swings and episodes of dizziness and lightheadedness. Despite a positive initial pregnancy test, a subsequent blood test by her doctor was negative. She has no changes in bowel movements, unusual weight gain or loss, unusual hair growth or loss, or other symptoms suggesting a hormonal imbalance. She has no pre-existing conditions, chronic illnesses, or family history of hormonal disorders or thyroid issues, and is not currently taking any medications other than the one prescribed for nausea.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Hormonal Imbalance: Hormonal fluctuations can cause a variety of symptoms, including breast tenderness, nausea, fatigue, mood swings, and changes in your menstrual cycle. Given that you had your tubes removed, it's less likely but not impossible to be pregnant. Hormonal imbalances can also be caused by stress, changes in weight, or other underlying conditions.

    • Typical Treatments: Hormonal imbalances are often diagnosed through blood tests. Treatment may include lifestyle changes, hormone therapy, or medications to manage specific symptoms.
  • Premenstrual Syndrome (PMS) or Premenstrual Dysphoric Disorder (PMDD): These conditions can cause symptoms similar to what you're experiencing, including breast tenderness, mood swings, fatigue, and cramps.

    • Typical Treatments: Treatment may include lifestyle changes, dietary adjustments, exercise, and medications such as pain relievers or hormonal treatments.
  • Thyroid Issues: Conditions like hypothyroidism or hyperthyroidism can cause fatigue, mood swings, and changes in your menstrual cycle.

    • Typical Treatments: Thyroid issues are diagnosed through blood tests. Treatment usually involves medication to regulate thyroid hormone levels.
  • Stress and Anxiety: High levels of stress and anxiety can manifest physically, causing symptoms like nausea, insomnia, fatigue, and mood swings.

    • Typical Treatments: Stress management techniques, counseling, and sometimes medications can help manage these symptoms.

What you can do

While it's important to consult a healthcare provider for a formal diagnosis and treatment plan, here are some steps you can take in the meantime:

  1. Keep a Symptom Journal: Use MDandMe to journal your symptoms, track your progress, and share longitudinal medical notes with your provider. This can help identify patterns and triggers.
  2. Maintain a Balanced Diet: Eating a nutritious, balanced diet can help manage symptoms like nausea and fatigue. Avoid foods that trigger nausea.
  3. Stay Hydrated: Drink plenty of water to stay hydrated, especially if you're feeling nauseous.
  4. Practice Stress Management: Techniques like deep breathing, meditation, and gentle exercise can help manage stress and anxiety.
  5. Get Adequate Rest: Try to establish a regular sleep routine to help with insomnia and fatigue.
  6. Over-the-Counter Pain Relief: For breast tenderness and cramps, over-the-counter pain relievers like ibuprofen or acetaminophen may help.

What you should look out for

Reasons to see a doctor more urgently include:

  • Severe or Worsening Symptoms: If your symptoms become more severe or do not improve with self-care measures.
  • New or Unexplained Symptoms: If you develop new symptoms that are unexplained or concerning.
  • Persistent Nausea and Vomiting: If you cannot keep food or liquids down.
  • Severe Mood Swings or Depression: If you experience severe mood swings or symptoms of depression.

Remember, while I can provide information and suggestions, it's important to seek care from real health professionals to receive a formal diagnosis and appropriate treatment.

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4 mo ago

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People Also Ask


What could be causing persistent breast pain and tenderness?

Persistent breast pain and tenderness can be caused by hormonal fluctuations, premenstrual syndrome (PMS), or other conditions like fibrocystic breast changes. It's important to consult a healthcare provider for a proper diagnosis.


How can hormonal imbalances affect my menstrual cycle and overall health?

Hormonal imbalances can lead to symptoms such as irregular menstrual cycles, mood swings, fatigue, and changes in appetite. They can be caused by stress, weight changes, or underlying health issues and are often diagnosed through blood tests.


What are some effective ways to manage stress and anxiety-related symptoms?

Effective ways to manage stress and anxiety include practicing relaxation techniques like deep breathing and meditation, engaging in regular physical activity, maintaining a balanced diet, and seeking counseling or therapy if needed.


When should I seek medical attention for symptoms like nausea and fatigue?

You should seek medical attention if your symptoms become severe, do not improve with self-care, or if you experience new or concerning symptoms. Persistent nausea and fatigue, especially if accompanied by an inability to keep food or liquids down, warrant a doctor's visit.


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