[33F] Experiencing severe tongue swelling and associated symptoms

Patient Description

A 33-year-old female presents with a swollen, painful tongue described as sharp and burning, particularly where teeth indentations are present. The swelling is more pronounced on the left side, with the tongue appearing purple/black in color. The patient has been managing with a straw due to difficulty swallowing for the past 2.5 days and has had trouble speaking for 4.5 days due to the inability to move the tongue normally. Excessive drooling has been noted for 5 days, with the patient unable to control or swallow it without effort and pain. Additionally, the patient reports stiff and visibly different lymph nodes on the left side of the neck compared to the right. The patient's medical history includes being auto-immune compromised, mental health concerns, and a tonsillectomy. The patient is allergic to all medications and is currently taking Vyvanse XR, Kyleena, Ambien XR, Clonidine, Requip, Lamictal, and Semaglutide.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Glossitis: This is inflammation of the tongue, which can cause swelling, changes in tongue color, and pain. It can be caused by various factors such as allergic reactions, infections, and certain chronic diseases.

    • Treatment typically involves addressing the underlying cause, and may include medications to reduce inflammation and pain.
  • Angioedema: This is a condition that can cause sudden swelling beneath the skin, often around the mouth and throat, which can affect the tongue. It can be caused by allergic reactions or certain medications, and is more common in people with autoimmune diseases.

    • Treatment typically involves medications to reduce swelling, such as antihistamines or corticosteroids.
  • Oral Thrush: This is a fungal infection in the mouth that can cause a painful, swollen tongue with a white or black coating. It's more common in people with weakened immune systems.

    • Treatment typically involves antifungal medications.

What you can do

Given the severity and duration of your symptoms, it's important to seek medical attention as soon as possible. In the meantime, try to stay hydrated and avoid foods or drinks that may irritate your tongue further, such as spicy or acidic foods. Over-the-counter pain relievers may also help manage your pain, but be sure to avoid any that you're allergic to.

What you should look out for

Seek immediate medical attention if you experience any of the following:

  • Difficulty breathing or shortness of breath
  • Rapid worsening of your symptoms
  • Inability to eat or drink due to your symptoms

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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11 mo ago

People Also Ask


What are the common causes of a swollen and painful tongue?

A swollen and painful tongue can be caused by various factors including allergic reactions, infections like oral thrush, nutritional deficiencies, trauma, or underlying health conditions such as autoimmune diseases.


How can autoimmune conditions affect oral health?

Autoimmune conditions can lead to oral health issues by causing inflammation, increasing susceptibility to infections, and affecting the body's ability to heal. This can result in symptoms like a swollen tongue, mouth ulcers, and dry mouth.


What are the symptoms and treatments for oral thrush?

Oral thrush is a fungal infection characterized by white or black patches on the tongue and inside the mouth, along with pain and swelling. Treatment typically involves antifungal medications prescribed by a healthcare provider.


When should I seek immediate medical attention for tongue swelling?

Immediate medical attention should be sought if you experience difficulty breathing, rapid worsening of symptoms, or an inability to eat or drink due to tongue swelling, as these could indicate a serious condition requiring urgent care.


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