[32F] Experiencing a constellation of symptoms including neuropathy and muscle weakness

What might be happening

Based on the information you've provided, it's difficult to pinpoint a single condition that could explain all of your symptoms. However, here are some possibilities:

• Fibromyalgia: This condition is characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. It is believed to amplify painful sensations by affecting the way your brain and spinal cord process painful and nonpainful signals. The fatigue, muscle weakness, joint pain, sleep disturbance, depression, and brain fog you're experiencing could be related to this condition.

  • There's no cure for fibromyalgia, but medication, exercise, stress management, and healthy habits might ease your symptoms.

• Chronic Fatigue Syndrome (CFS): This is a complicated disorder characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue worsens with physical or mental activity, but doesn't improve with rest. This could explain your fatigue, muscle weakness, joint pain, sleep disturbance, depression, and brain fog.

  • There's no single test to confirm a diagnosis of chronic fatigue syndrome. Treatment focuses on symptom relief.

• Eosinophilic Granulomatosis with Polyangiitis (EGPA): This is a rare disorder that causes inflammation in small and medium-sized blood vessels in people who have a history of airway allergic hypersensitivity (atopy). You mentioned that you have been diagnosed with EGPA without granulomas. Some of your symptoms like neuropathy, skin changes, and gastrointestinal problems could be related to this condition.

  • Treatment usually involves corticosteroids and other immune-suppressing drugs.

• Side effects of medication: Some of your symptoms might be side effects of the medications you're taking. For example, Cymbalta can cause dizziness, weight gain, and sleep disturbance. Methotrexate can cause fatigue and hair loss.

What you can do

Given the complexity and range of your symptoms, it's important that you seek medical attention. Here are some steps you can take:

1. Schedule an appointment with your primary care doctor. They can help coordinate your care and refer you to specialists if needed.
2. Keep a symptom diary. This can help you and your doctor understand your symptoms better and identify any patterns or triggers.
3. Take care of your mental health. Consider seeking help from a mental health professional if you're feeling depressed.
4. Stay active. Regular physical activity can help manage symptoms like fatigue and joint pain.
5. Eat a balanced diet. This can help support your overall health and wellbeing.

What you should look out for

Seek immediate medical attention if you experience:

• Severe pain
• Difficulty breathing
• Sudden worsening of any of your symptoms

Remember, while I strive to provide accurate information, I'm not a doctor. Always consult with a healthcare professional for a formal diagnosis and treatment.