[31F] With abdominal pain, constipation, and bloating post-semaglutide cessation

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

• Post-Semaglutide Withdrawal: Semaglutide is a medication often used for weight loss, and stopping it can sometimes lead to gastrointestinal symptoms like constipation, bloating, and changes in bowel habits. Your body might be adjusting to the absence of the medication.

  • Treatment: This usually involves supportive care, such as dietary adjustments and over-the-counter remedies to manage symptoms. Your doctor might also suggest a gradual tapering off the medication if you need to restart it.

• Irritable Bowel Syndrome (IBS): IBS is a common condition that affects the large intestine and can cause symptoms like abdominal pain, bloating, constipation, and diarrhea. Stress and dietary factors can often exacerbate these symptoms.

  • Treatment: Management typically includes dietary changes (like increasing fiber intake), stress management techniques, and sometimes medications to relieve specific symptoms.

• Constipation: Chronic constipation can lead to bloating and abdominal pain. This can be due to dietary factors, lack of physical activity, or changes in routine.

  • Treatment: Increasing fiber intake, staying hydrated, and regular physical activity can help. Over-the-counter laxatives may also be useful, but it's best to consult a healthcare provider for long-term management.

• Post-Surgical Changes: Given your history of gastric sleeve surgery, changes in your digestive system could be contributing to your symptoms. This surgery can sometimes lead to altered bowel habits and nutrient absorption issues.

  • Treatment: Follow-up with your bariatric surgeon or a gastroenterologist may be necessary to ensure that there are no complications from the surgery.

What you can do

While it's important to consult a healthcare provider for a formal diagnosis and treatment plan, here are some steps you can take to manage your symptoms:

1. Dietary Adjustments: Increase your fiber intake gradually by eating more fruits, vegetables, and whole grains. This can help with constipation and bloating.
2. Hydration: Drink plenty of water throughout the day to help soften your stool and make it easier to pass.
3. Physical Activity: Regular exercise can help stimulate bowel movements and reduce bloating.
4. Over-the-Counter Remedies: Consider using over-the-counter laxatives or stool softeners for short-term relief of constipation. Always follow the instructions on the label.
5. Symptom Tracking: Use MDandMe to journal your symptoms, track your progress, and get insights. This can be very helpful when you discuss your symptoms with your healthcare provider.
6. Avoid Trigger Foods: Even though you haven't identified specific triggers, it might be helpful to avoid foods that are known to cause bloating and constipation, such as processed foods, dairy, and high-fat foods.

What you should look out for

Seek medical attention if you experience any of the following:

• Severe or worsening abdominal pain
• Blood in your stool
• Unexplained weight loss
• Persistent vomiting or inability to keep food down
• Fever or chills
• Symptoms that do not improve with over-the-counter treatments or dietary changes

Remember, while these suggestions can help manage your symptoms, it's crucial to consult a healthcare provider for a formal diagnosis and personalized treatment plan.