[29F] With rectal bleeding, cramping, and fatigue

Patient Description

A 29-year-old female presents with rectal bleeding, characterized by blood clots and bright red blood, occurring multiple times a day for the past 4 days. The bleeding started suddenly and is accompanied by moderate lower belly cramping that worsens with sitting, standing, eating, and not eating. The patient also reports fatigue, changes in bowel habits (both diarrhea and constipation), unintentional weight loss, nausea, and vomiting. There is no fever, chills, or black/tarry stool. The patient experiences pain or discomfort in the rectal area. She has a family history of polyps, IBS, and pancreatic cancer. The patient has no history of gastrointestinal conditions and has not recently started or changed any medications. She does not use alcohol, tobacco, or recreational drugs. She was diagnosed with PCOS 4 years ago and is currently taking Labetalol (200mg twice a day) for blood pressure and Zoloft for anxiety. No known drug allergies.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

Rectal Bleeding with Blood Clots, Cramping, and Fatigue

  1. Hemorrhoids or Anal Fissures:

    • Rationale: Bright red blood and pain during bowel movements can be indicative of hemorrhoids or anal fissures. These are common and can cause significant discomfort and bleeding.
    • Typical Treatments: Over-the-counter creams, sitz baths, and increased fiber intake. In severe cases, medical procedures may be necessary.
  2. Inflammatory Bowel Disease (IBD):

    • Rationale: Conditions like Crohn's disease or ulcerative colitis can cause rectal bleeding, cramping, and changes in bowel habits. While you don't have a history of these, they can develop later in life.
    • Typical Treatments: Anti-inflammatory medications, immune system suppressors, and sometimes surgery. Diagnosis typically involves colonoscopy and imaging studies.
  3. Gastrointestinal Infections:

    • Rationale: Infections can cause sudden onset of symptoms like diarrhea, cramping, and rectal bleeding.
    • Typical Treatments: Antibiotics or antiviral medications, depending on the cause. Stool tests are often used for diagnosis.

Unifying Diagnoses

  1. Colorectal Polyps or Cancer:

    • Rationale: Given your family history of polyps and pancreatic cancer, and the presence of rectal bleeding and weight loss, this is a concern that needs to be ruled out.
    • Typical Treatments: Colonoscopy for diagnosis, followed by surgical removal, chemotherapy, or radiation therapy if necessary.
  2. Irritable Bowel Syndrome (IBS):

    • Rationale: While IBS typically doesn't cause rectal bleeding, it can cause cramping, changes in bowel habits, and fatigue. It might be co-occurring with another condition.
    • Typical Treatments: Dietary changes, stress management, and medications to manage symptoms.

What you can do

Rectal Bleeding and Cramping

  • See a doctor as soon as possible: Given the severity and sudden onset of your symptoms, it's important to get a professional evaluation. Your doctor may recommend a colonoscopy or other diagnostic tests.
  • At home:
    • Increase your fiber intake to help with bowel movements.
    • Stay hydrated to prevent constipation.
    • Avoid straining during bowel movements.
    • Use over-the-counter pain relief like acetaminophen (Tylenol) for cramping, but avoid NSAIDs like ibuprofen as they can worsen bleeding.

Fatigue

  • Consult your doctor: Fatigue can be a symptom of many underlying conditions, including anemia from blood loss.
  • At home:
    • Ensure you get adequate rest.
    • Maintain a balanced diet rich in iron and vitamins.
    • Track your energy levels and activities using the MDandMe journal to identify patterns and triggers.

What you should look out for

Given the severity of your symptoms and the possibility of serious underlying conditions, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Increased bleeding: If you notice a significant increase in the amount of blood, or if the bleeding doesn't stop.
  • Severe pain: If your pain becomes unbearable or is accompanied by fever.
  • Signs of anemia: Such as dizziness, shortness of breath, or paleness.
  • Changes in stool color: If your stool becomes black or tarry, which can indicate internal bleeding.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment. You can use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

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People Also Ask


What could cause sudden rectal bleeding with blood clots and cramping?

Sudden rectal bleeding with blood clots and cramping can be caused by conditions such as hemorrhoids, anal fissures, inflammatory bowel disease (IBD), gastrointestinal infections, or colorectal polyps or cancer. It's important to consult a healthcare professional for an accurate diagnosis.


How can family history of polyps and cancer affect my current symptoms?

A family history of polyps and cancer can increase the risk of similar conditions, such as colorectal cancer, which can present with symptoms like rectal bleeding and weight loss. It's important to discuss your family history with your doctor, who may recommend screening tests like a colonoscopy.


What are the potential treatments for inflammatory bowel disease (IBD)?

Treatments for inflammatory bowel disease (IBD) typically include anti-inflammatory medications, immune system suppressors, and sometimes surgery. Diagnosis usually involves a colonoscopy and imaging studies to determine the extent and type of IBD.


How can I manage fatigue associated with rectal bleeding and cramping?

To manage fatigue associated with rectal bleeding and cramping, ensure you get adequate rest, maintain a balanced diet rich in iron and vitamins, and stay hydrated. It's also important to consult your doctor, as fatigue can be a symptom of anemia from blood loss.


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