[29F] With abnormal vaginal discharge post-unprotected intercourse

Patient Description

A 29-year-old female experienced abnormal vaginal discharge starting the day after unprotected intercourse. The discharge was initially thick and white, now clear with white specks, and has slightly decreased. There is no associated smell, itching, burning, irritation, or pelvic pain. The patient had a brief episode of nausea but no fever or swollen lymph nodes. Recent STI tests were negative, possibly due to early testing. The patient is currently on Doxycycline Hyclate 100 mg twice daily and Metronidazole Gel 0.75% nightly. No chronic illnesses reported. Allergic to penicillin. The patient's last menstrual period was heavier than usual, and no new products or medications have been used recently.

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Arora's Assessment

What might be happening

Based on your symptoms and recent unprotected sexual activity, here are some possibilities:

  • Bacterial Vaginosis (BV): This is a common vaginal infection that can cause abnormal discharge. It often doesn't have a strong odor and can be treated with antibiotics like Metronidazole.

  • Sexually Transmitted Infections (STIs): Some STIs, such as chlamydia or gonorrhea, can cause changes in vaginal discharge. It's possible that initial tests were too early to detect an infection.

  • Yeast Infection: Although less likely given the lack of itching or irritation, yeast infections can cause changes in discharge.

Your doctor has prescribed Doxycycline and Metronidazole, which are commonly used to treat bacterial infections, including BV and certain STIs.

What you can do

  1. Complete Your Medication: Continue taking the prescribed medications as directed by your doctor.

  2. Follow Up: Consider getting retested for STIs in a week or so, as your doctor suggested it might be too early to detect an infection.

  3. Communicate with Your Partner: If possible, discuss STI testing with your partner to ensure both of you are informed and treated if necessary.

  4. Track Symptoms: Use MDandMe to journal your symptoms, track progress, and share insights with your healthcare provider.

What you should look out for

  • Worsening Symptoms: If you notice any new symptoms like itching, burning, or a strong odor, contact your healthcare provider.

  • Persistent Discharge: If the discharge doesn't improve after completing your medication, follow up with your doctor.

  • Fever or Pain: Seek medical attention if you develop a fever, pelvic pain, or any other concerning symptoms.

Remember, it's important to consult with a healthcare professional for a formal diagnosis and treatment.

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2 mo ago


People Also Ask


What are the common symptoms of bacterial vaginosis (BV)?

Common symptoms of bacterial vaginosis include abnormal vaginal discharge that may be thin and grayish-white, a fishy odor, especially after intercourse, and sometimes mild irritation or itching. However, some women may not experience any symptoms.


How soon after exposure can sexually transmitted infections (STIs) be detected?

The detection window for STIs varies. For example, chlamydia and gonorrhea can often be detected within 1-2 weeks after exposure, but it may take longer for some tests to show positive results. It's important to follow up with your healthcare provider for retesting if initial tests were done too early.


Can a yeast infection occur without itching or irritation?

Yes, a yeast infection can occur without the typical symptoms of itching or irritation. Some women may only notice changes in discharge, such as a thick, white, cottage cheese-like consistency.


What should I do if my symptoms persist after completing the prescribed medication?

If your symptoms persist after completing the prescribed medication, it's important to follow up with your healthcare provider. They may recommend further testing or a different treatment approach to address the underlying issue.


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