[28F] With cramping pain underneath rib cage and major nausea

What might be happening

Based on the symptoms you've described and your medical history, here are some possible explanations:

1. Gastrointestinal Issues:

   • Gastritis or Peptic Ulcer: These conditions can cause cramping pain in the upper abdomen and nausea. They are often exacerbated by stress, certain foods, or medications.
   • Gastroesophageal Reflux Disease (GERD): This condition can cause heartburn and cramping pain under the rib cage, along with nausea.

2. Kidney-Related Issues:

   • Polycystic Kidney Disease (PKD): Given your history of PKD and recent decrease in GFR, it's possible that your kidney function is contributing to your symptoms. Kidney issues can sometimes cause referred pain to the upper abdomen and nausea.

3. Medication Side Effects:

   • Some of the medications you are taking, such as gabapentin, can cause gastrointestinal side effects, including nausea and cramping.

4. Pancreatitis:

   • Inflammation of the pancreas can cause severe upper abdominal pain that radiates to the back, along with nausea and vomiting. This is less likely given the absence of vomiting, but it is still a consideration.

What you can do

Cramping Pain and Nausea:

• See a Doctor: Given the severity and persistence of your symptoms, it is important to consult a healthcare provider as soon as possible. They may recommend blood tests, imaging studies, or other diagnostic tests to determine the cause of your symptoms.
• Dietary Adjustments: Avoid foods and beverages that can irritate your stomach, such as spicy foods, caffeine, and alcohol. Eating smaller, more frequent meals may also help.
• Medications: Continue taking Tylenol for pain relief, but avoid taking it in excess. Your doctor may prescribe medications to reduce stomach acid or treat any underlying gastrointestinal issues.
• Hydration: Ensure you stay well-hydrated, especially if you are experiencing diarrhea. Drink plenty of water and consider oral rehydration solutions if needed.

Kidney Health:

• Monitor Symptoms: Keep track of any changes in your symptoms, such as increased pain, changes in urine output, or swelling. Use the MDandMe journal to document these changes and share them with your healthcare provider.
• Follow-Up: Regularly follow up with your nephrologist to monitor your kidney function and discuss any changes in your condition.

What you should look out for

Given your symptoms and medical history, you should seek medical care urgently if you experience any of the following:

• Severe or worsening pain
• Vomiting that prevents you from keeping down fluids
• Signs of dehydration, such as dry mouth, decreased urine output, or dizziness
• Blood in your stool or vomit
• Jaundice (yellowing of the skin or eyes)
• Any new or worsening symptoms related to your kidney function, such as swelling, changes in urine output, or shortness of breath

Remember, while I can provide information and suggestions, it is crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment. If you have any more questions or need further assistance, feel free to continue the conversation.