[28F] Experiencing persistent fatigue, high WBC and platelet counts, and recurrent infections

Patient Description

A 28-year-old female presents with extreme fatigue, high white blood cell count, high platelet count, and recurrent illnesses including frequent colds and ear infections. The fatigue is severe, with the patient sleeping throughout the day and night yet still feeling tired. This has been ongoing for a month and is exacerbated by physical activities such as walking and cooking. The patient also experiences night sweats every other night and a feeling of fullness in the ears that started two days ago. Additionally, there is a report of chills, pain on the sides of the neck, and a history of unexplained bruising prior to the onset of these symptoms. The patient has a family history of cancer and has been experiencing bone pain. No weight loss, swollen glands, or fever has been reported. The patient's condition severely impacts daily functioning.

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Arora's Assessment

What might be happening

Based on the information provided, several conditions could be causing your symptoms:

  • Chronic Fatigue Syndrome (CFS): This condition is characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue worsens with physical or mental activity, but doesn't improve with rest. This condition is also known as myalgic encephalomyelitis (ME) or systemic exertion intolerance disease (SEID).

    • There's no single test to confirm a diagnosis of chronic fatigue syndrome. You may need a variety of medical tests to rule out other health problems that have similar symptoms. Treatment for chronic fatigue syndrome focuses on symptom relief.
  • Anemia: This is a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues. Having anemia can make you feel tired and weak. There are many forms of anemia, each with its own cause.

    • Treatment depends on the kind of anemia you have.
  • Infectious Mononucleosis: This is a viral infection causing symptoms including a sore throat, fever, and fatigue. It is often spread by saliva and close contact.

    • Treatment involves rest and adequate fluids. In some cases, a course of antiviral medications may be needed.
  • Thyroid Disorders: The thyroid gland produces hormones that control the body's metabolism. If the thyroid produces too much hormone (hyperthyroidism), or not enough (hypothyroidism), fatigue and weakness can result.

    • Treatment depends on whether your thyroid is overactive or underactive.
  • Sleep Disorders: Conditions such as sleep apnea can cause chronic fatigue and are often undiagnosed.

    • Treatment can include lifestyle changes, mouthpieces, breathing devices, and surgery.
  • Depression: This is a mood disorder that causes a persistent feeling of sadness and loss of interest. It can cause physical symptoms such as fatigue and lack of energy.

    • Treatment usually involves medication, psychotherapy or a combination of the two.

What you can do

  1. Consult a healthcare professional: It's important to seek medical attention to get a proper diagnosis and treatment.

  2. Keep a symptom diary: This can help you track your symptoms and identify any patterns or triggers. This information can be helpful to your healthcare provider.

  3. Rest and take care of yourself: Make sure you're getting enough sleep, eating a healthy diet, and taking time to relax and take care of yourself.

  4. Stay hydrated: Drink plenty of fluids, especially water, to stay hydrated.

  5. Avoid alcohol and caffeine: These can interfere with your sleep and increase feelings of fatigue.

What you should look out for

  • If your symptoms get worse or you develop new symptoms
  • If you have difficulty breathing or chest pain
  • If you have severe pain, especially in your chest, abdomen or head
  • If you have a high fever, severe headache, stiff neck, or sensitivity to light
  • If you are unable to eat or drink, or if you're losing weight without trying
  • If you feel confused, disoriented, or have difficulty staying awake

Remember, I'm an AI and this advice is based on the information you've given me. It's always a good idea to consult with a healthcare professional for a formal diagnosis and treatment.

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10 mo ago

People Also Ask


What could cause extreme fatigue and high white blood cell count?

Extreme fatigue and a high white blood cell count can be caused by several conditions, including infections, chronic fatigue syndrome, thyroid disorders, or even more serious conditions like leukemia. It's important to consult a healthcare professional for a proper diagnosis.


How can recurrent illnesses like frequent colds and ear infections be related to fatigue?

Recurrent illnesses such as frequent colds and ear infections can weaken the immune system, leading to fatigue. Additionally, underlying conditions like chronic fatigue syndrome or an immune system disorder could contribute to both fatigue and frequent infections.


What are the potential implications of a high platelet count?

A high platelet count, known as thrombocytosis, can be a reaction to an infection, inflammation, or more serious conditions like bone marrow disorders. It requires further investigation by a healthcare provider to determine the underlying cause.


How does a family history of cancer affect the assessment of these symptoms?

A family history of cancer can increase the risk of certain types of cancer, which may be considered when assessing symptoms like unexplained bruising and bone pain. However, these symptoms can also be related to other non-cancerous conditions, so a thorough evaluation by a healthcare professional is necessary.


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