[27F] With chronic knee pain and arthritis concerns

Patient Description

A 27-year-old female presents with chronic knee pain persisting for two years, rated as 5 out of 10 in severity. The pain is localized to the inner corner and across the center of the knee, exacerbated by activities such as walking on inclines, climbing stairs, bending, squatting, and prolonged walking. The patient reports associated symptoms of swelling, stiffness, warmth, redness, and occasional locking or instability in the knee. She has tried various treatments including Tylenol, Ibuprofen, Voltarin Cream, and knee braces, with limited relief. The patient also experiences lower leg tenderness, occasional numbness, and severe numbness and swelling in both hands, potentially related to carpal tunnel syndrome. Her family history is significant for arthritis in both parents and a sister, with her father's condition being particularly severe. Medical history includes chronic hypertension, obesity, multiple stage arthritis of the spine, degenerative disc disease, carpal tunnel syndrome, and an ovarian cyst, all diagnosed in 2022. She takes ibuprofen, 800mg three times daily, and has a dairy allergy. Knee imaging tests were performed but did not include standing X-rays.

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Arora's Assessment

What might be happening

Based on the symptoms and history you've provided, there are a few possible explanations for your knee pain and related symptoms:

  1. Osteoarthritis: Given your family history and the symptoms of pain, swelling, stiffness, and cracking sounds in your knee, osteoarthritis is a likely cause. This condition involves the wearing down of the cartilage in your joints, leading to pain and stiffness. The fact that your spine is already affected by arthritis supports this possibility. Typical treatments include pain management with medications like NSAIDs, physical therapy, and in some cases, joint injections or surgery.

  2. Patellofemoral Pain Syndrome: This condition is characterized by pain around the kneecap and is often exacerbated by activities like climbing stairs or squatting. It can cause a grinding sensation and is often related to muscle imbalances or alignment issues. Treatment typically involves physical therapy to strengthen the muscles around the knee and improve alignment.

  3. Degenerative Joint Disease: This is a broader term that includes osteoarthritis and involves the degeneration of joint cartilage and the underlying bone. It can cause similar symptoms to those you're experiencing and is often managed with lifestyle modifications, medications, and physical therapy.

Your symptoms of lower leg tenderness, numbness, and swelling in your hands could be related to your carpal tunnel syndrome or other nerve-related issues, possibly exacerbated by your degenerative disc disease.

What you can do

Knee Pain:

  • Consider consulting with an orthopedic specialist or a physical therapist for a comprehensive evaluation and personalized treatment plan.
  • Continue using over-the-counter pain relief like ibuprofen, but be cautious of long-term use and potential side effects. Discuss with your doctor if a different medication might be more appropriate.
  • Apply ice packs to your knee to reduce swelling and pain after activities.
  • Engage in low-impact exercises, such as swimming or cycling, to maintain joint mobility without putting too much strain on your knees.
  • Use knee braces or supports to provide stability during activities.

General Health:

  • Work on weight management strategies, as reducing weight can significantly decrease the stress on your knees and improve overall joint health.
  • Consider dietary changes that include anti-inflammatory foods, such as fruits, vegetables, and omega-3 fatty acids, which may help reduce joint inflammation.
  • Use MDandMe to journal your symptoms, track progress, and share insights with your healthcare provider.

What you should look out for

  • If you experience increased swelling, redness, or warmth in your knee, or if the pain becomes severe and unmanageable, seek medical attention promptly.
  • Be aware of any new or worsening symptoms, such as significant changes in mobility or function, and discuss these with your healthcare provider.
  • Monitor for any side effects from medications, especially if you are taking ibuprofen regularly, and consult your doctor if you have concerns.

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and personalized treatment plan.

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2 mo ago

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People Also Ask


What are the common symptoms of osteoarthritis in the knee?

Common symptoms of osteoarthritis in the knee include pain, swelling, stiffness, a grating sensation during movement, and decreased range of motion. These symptoms often worsen with activity and improve with rest.


How can patellofemoral pain syndrome be managed effectively?

Patellofemoral pain syndrome can be managed with physical therapy focused on strengthening the muscles around the knee, improving alignment, and correcting muscle imbalances. Avoiding activities that exacerbate the pain, using knee braces, and applying ice can also help.


What lifestyle changes can help manage degenerative joint disease?

Lifestyle changes that can help manage degenerative joint disease include maintaining a healthy weight to reduce stress on the joints, engaging in regular low-impact exercises like swimming or cycling, and incorporating anti-inflammatory foods into the diet.


What are the potential side effects of long-term ibuprofen use?

Long-term use of ibuprofen can lead to side effects such as gastrointestinal issues (like ulcers or bleeding), kidney damage, increased blood pressure, and an increased risk of heart attack or stroke. It's important to use it under medical supervision and explore alternative pain management options if necessary.


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