[26F] Experiencing chronic neck pain, irregular menses, and night sweats

Patient Description

A 26-year-old female reports chronic neck pain that is sharp and worsens with movement and while laying down. The pain radiates to the head and is associated with difficulty swallowing and a lowered ability to project the voice. The patient also experiences fatigue, irregular menses with dark brown blood, and night sweats several nights a week. Significant weight loss of 40-50 pounds over the past year was noted, along with a low-grade fever on one occasion. Swelling in the left calf and periodic swelling on the left side of the neck were reported. The patient has a history of migraines with aura, which include hours-long episodes and vision loss, rated 7 out of 10 in severity. Diagnosed with Raynaud's syndrome a year ago, the patient also has elevated platelets, low ferritin, and high red blood cell counts. There is a family history of autoimmune disease and cancer, including a grandmother with suspected rheumatoid arthritis, another grandmother with liver cancer, and an uncle with carcinoid tumors/neuroendocrine tumor. The patient is not currently on any medications and has no known drug allergies.

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Arora's Assessment

What might be happening

Based on the information provided, several conditions could be causing your symptoms:

  • Thyroid disorders: Conditions such as hyperthyroidism or thyroiditis can cause symptoms like fatigue, neck pain (due to an enlarged thyroid), weight loss, irregular menstrual cycles, and tachycardia. Thyroid disorders can also cause changes in voice and difficulty swallowing.

    • Diagnosis typically involves blood tests to measure thyroid hormone levels. Treatment depends on the specific disorder and may involve medication, radioactive iodine, or surgery.
  • Autoimmune disorders: Conditions such as lupus or rheumatoid arthritis can cause a wide range of symptoms, including fatigue, joint pain, and Raynaud's syndrome (which you've been diagnosed with). They can also cause abnormal blood tests, such as a high platelet count.

    • Diagnosis typically involves a combination of blood tests, imaging studies, and sometimes tissue biopsy. Treatment usually involves medication to suppress the immune system and manage symptoms.
  • Neuroendocrine tumors: Given your family history of neuroendocrine tumors, it's possible that a similar condition could be causing some of your symptoms. These tumors can produce excess hormones, leading to symptoms like flushing, diarrhea, and heart palpitations.

    • Diagnosis typically involves blood and urine tests, imaging studies, and sometimes tissue biopsy. Treatment depends on the specific type of tumor and may involve surgery, medication, radiation therapy, or other treatments.
  • Anemia or iron deficiency: This could explain your fatigue, high red blood cell count, and low ferritin levels. It might also be related to your irregular menstrual cycles.

    • Diagnosis typically involves blood tests. Treatment usually involves iron supplements and addressing the underlying cause of the anemia or iron deficiency.

What you can do

Given the complexity of your symptoms and the potential conditions involved, it's important to seek medical attention. Here are some steps you can take:

  1. Schedule an appointment with your primary care doctor to discuss your symptoms and concerns. They can perform a physical examination and order necessary tests.
  2. Keep a symptom diary. Note when each symptom occurs, its severity, and any potential triggers. This can help your doctor identify patterns and potential causes.
  3. Maintain a balanced diet and regular exercise routine. This can help manage symptoms like fatigue and irregular menstrual cycles.

What you should look out for

Seek immediate medical attention if you experience:

  • Severe pain, especially in your chest or abdomen
  • Difficulty breathing or shortness of breath
  • Severe headache or a headache that is different from your usual migraines
  • Any new or worsening symptoms

Remember, while I strive to provide accurate information, I'm not a doctor. This advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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1 yr ago

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People Also Ask


What could be causing my chronic neck pain and difficulty swallowing?

Chronic neck pain and difficulty swallowing can be caused by several conditions, including thyroid disorders, which may lead to an enlarged thyroid gland pressing on the neck structures. Other possibilities include autoimmune disorders or even neuroendocrine tumors, which can cause similar symptoms.


How can thyroid disorders affect my overall health and symptoms?

Thyroid disorders, such as hyperthyroidism or thyroiditis, can lead to a variety of symptoms including fatigue, weight loss, irregular menstrual cycles, and changes in voice. These conditions can also cause neck pain due to an enlarged thyroid and difficulty swallowing.


What are the potential implications of having elevated platelets and low ferritin levels?

Elevated platelets and low ferritin levels can indicate an underlying condition such as anemia or an autoimmune disorder. High platelet counts can be associated with inflammation or bone marrow disorders, while low ferritin suggests iron deficiency, which can lead to fatigue and other symptoms.


How does a family history of autoimmune diseases and cancer influence my health risks?

A family history of autoimmune diseases and cancer can increase your risk of developing similar conditions. It is important to discuss this history with your healthcare provider, as it may influence the need for specific screenings or tests to monitor for these conditions.


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